This dataset includes chemical, meteorological, physical time series data collected from BOBOA_90E_15N deployments in the Bay of Bengal, Indian Ocean from 2013-11-24 to 2018-11-20. These data include mole fraction of CO2 in air in equilibrium with the seawater at sea surface temperature and measured humidity, mole fraction of H2O in air from equilibrator, mole fraction of CO2 in air from airblock, 4 feet above the sea surface at measured humidity, mole fraction of H2O in air from airblock, 4 feet above the sea surface, atmospheric pressure, temperature of the Infrared Licor 820 in degrees Celsius, the percent oxygen of the surface seawater divided by the percent oxygen of the atmosphere, sea surface temperature, sea surface salinity, mole fraction of CO2 in air in equilibrium with the seawater at sea surface temperature (dry air), fugacity of CO2 in air in equilibrium with the seawater at sea surface temperature (100% humidity), difference of the fugacity of the CO2 in seawater and the fugacity of the CO2 in air (fCO2 SW - fCO2 Air), pressure of CO2 in air in equilibrium with the seawater at sea surface temperature (100% humidity), partial pressure of CO2 in air at the airblock, the difference of the partial pressure of CO2 in seawater and air (pCO2 SW - pCO2 Air and pH of seawater (total scale), total chlorophyll, nephelometric turbidity unit and salinity-compensated dissolved oxygen. The Moored Autonomous pCO2 (MAPCO2®) instruments used to collect these data include Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer, Humidity Sensor, and oxygen meter. The Bay of Bengal Ocean Acidification (BOBOA) moored buoy was deployed at 15N, 90E on 23 November 2013 from the Indian Research Vessel Sagar Nidhi. This is the first CO2 flux and ocean acidification mooring in the northern Indian Ocean. Data from the buoy will help us understand the large intraseasonal, seasonal and interannual biogeochemical variations in the Bay of Bengal, and track how the marine ecosystem in the Bay is changing over time. Establishment of this time series was only possible through a close partnership between the Bay of Bengal Large Marine Ecosystem Project (BOBLME), with funding support from the Norwegian Agency for Development Cooperation, NOAA Ocean Acidification Program, the Research Moored Array for African-Asian-Australian Monsoon Analysis and Prediction (RAMA), NOAA Pacific Marine Environmental Laboratory, the Indian National Centre for Ocean Information Services, and the National Institute of Ocean Technology.