This dataset contains water temperature, salinity, oxygen, and other parameters taken by CTD and Niskin bottle samples in the Atlantic and Pacific Oceans. It combines 26 original submissions. Seabird 911plus systems equipped with dual temperature-conductivity-oxygen sensors were employed. All systems had a 24-bottle water sampling rosette with 10 liter Niskin bottles. Water sampling, processing, and calibration followed GO-SHIP recommendations (Swift, 2010; McTaggart et al., 2010; Uchida et al., 2010) and included the recommended steps Data Conversion, Sensor Time-Alignment, Creation of Bottle Files, Outlier Removal, Pressure Sensor Filtering, Conductivity Cell Thermal Mass Correction, Ship Roll Correction and Deck Offset Correction by Loop Editing, and Derivation of Calculated Properties. After these steps conductivity and oxygen readings were calibrated against values determined with salinometry and Winkler titration, respectively. Finally the downcast data was averaged over 1 dbar wide intervals. In addition to the CTDO measurements basically all CTDO casts included either a Dr. Haardt or a Wetlabs FLNTU fluorometer for CHL-a fluorescence. Several other sensors, such as a Wetlabs CDOM fluorometer and turbidity sensor, a Wetlabs C-Star transmissometer, a Photosynthetically Active Radiation (PAR) sensor manufactured by Biospherical Instruments, or a Seabird/Satlantic Submersible Ultraviolet Nitrate Analyzer (SUNA) have been attached to the CTDO system on some of the cruises or casts, depending on the availability of the sensors and their depth ratings. SUNA data were processed and calibrated following the procedures outlined in Sakamoto et al. (2009) and Sakamoto et al. (2017). To CHL-a and CDOM fluorescence, turbidity, transmissometer beam attenuation, and PAR data generally only the manufacturer’s calibration was applied in the stored files. Data are in ASCII format. Some data are duplicated as NetCDF.