Lung Bioassay of Ground Dwelling Mammals from the Grand Canyon Uranium Breccia Pipe Region Using Scanning Electron Microscopy
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Small mammal lung tissue sections were examined to help assess the effects of weathering on bioavailability and toxicity from sites in different phases of the mine cycle within the Grand Canyon area. Hematoxylin and eosin slides of lung tissue from brush mouse, deer mice, and pocket gophers were examined by a veterinary pathologist who marked areas of the tissue that showed normal, inflammation, bronchiolar hyperplasia, mineralization, intracellular refractile debris, macrophages, and parasitic pathology. These selected areas were examined with scanning electron microscopy and energy dispersive spectroscopy to determine the size and composition of particulate matter, if present, in these areas.
Hematoxylin and Eosin Slides of Lung Tissue from Ground Dwelling Mammals from the Grand Canyon Uranium Breccia Pipe Region
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Hematoxylin and eosin slides of lung tissue from brush mouse, deer mice, and pocket gophers were examined by a veterinary pathologist who marked areas of the tissue that showed normal, inflammation, bronchiolar hyperplasia, mineralization, intracellular refractile debris, macrophages, and parasitic pathology.
Results from radiochemical analyses of small rodent whole bodies collected from breccia pipe uranium mines and reference locations in the Grand Canyon watershed.
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These data are comprised of measurements of gross alpha activity, gross beta activity, and radionuclide activities (isotopic U, isotopic Th, Ra-226) in small rodent bodies. Samples were collected at non-mining and U breccia pipe mining sites in various production stages, in the Grand Canyon watershed.
LT3 Peat Smoke Extract Aspiration - All data
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Raw data for all figures and supplementary figures. This dataset is associated with the following publication: Thompson, L., Y. Kim, B. Martin, A. Ledbetter, J. Dye, M. Hazari, I. Gilmour, and A. Farraj. Pulmonary Exposure to Peat Smoke Extracts in Rats Decreases Expiratory Time and Increases Left Heart End Systolic Volume. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 30(11-12): 439-447, (2019).
Peat Smoke High Fat All data Feb2018.xlsx
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The data set is an excel spreadsheet containing all the raw data used to generate the tables and figures in the manuscript. This dataset is associated with the following publication: Martin, B., L. Thompson, Y. Kim, W. Williams, S. Snow, M. Schladweiler, P. Phillips, C. King, J. Richards, N. Coates, M. Higuchi, I. Gilmour, U. Kodavanti, M. Hazari, and A. Farraj. Acute Peat Smoke Inhalation Sensitizes Rats to the Postprandial Cardiometabolic Effects of a High Fat Oral Load. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 643: 378-391, (2018).