General aggregate PFOS and PFOA exposure estimates are based on reported summary statistics from concentration studies by media, i.e. into indoor air, outdoor air, food, water, dust and soil, and published contact rates. These values were entered into a first-order PK model to estimate PFOS and PFOA blood serum concentrations. which were then compared measured concentrations reported by the 2013-2014 National Health and Nutrition Examination Survey (NHANES) measured concentrations. These methods are an expansion of the process taken by two previous studies, which predicted body burden from aggregate route intakes for PFOA and for PFOS, respectively. This dataset is associated with the following publication: East, A., P. Egeghy, E. Hubal, R. Slover, and D. Vallero. Computational estimates of daily aggregate exposure to PFOA/PFOS from 2011 to 2017 using a basic intake model. Journal of Exposure Science and Environmental Epidemiology. Nature Publishing Group, London, UK, 33: 56-68, (2023).

We used systematic evidence map methods to summarize the available epidemiological and animal bioassay evidence for an expanded set of ~15,000 PFAS that were identified as PFAS by EPA's Center for Computational Toxicology and Exposure (CCTE). This work is a continuation of our previous 2022 and 2024 SEMs that inventoried evidence on a separate set of ~500 PFAS (Carlson et al, 2022, https://doi.org/10.1289/EHP10343; Radke et al, 2022, https://doi.org/10.1289/EHP11185; Carlson et al., 2024; https://doi.org/10.1289/EHP14191) and a 2023 evidence map on an additional 345 PFAS (Shirke et al. 2024, https://doi.org/10.1289/EHP13423 ). The comprehensive PFAS dashboard includes evidence identified from our past SEMs and completed US EPA assessments. This dataset is associated with the following publication: Shirke, A., E. Radke, R. Jones, B. Allen, C. Lin, A. Ross, N. Vetter, C. Lemeris, p. hartman, S. Eftim, A. Varghese, R. Blain, H. Hubbard, A. Williams, K. Thayer, and L. Carlson. Systematic Evidence Map for the Per- and Polyfluoroalkyl Substances (PFAS) Universe. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 0(0): 1-45, (2025).

This file contains data from accumulation of chloro perfluoro polyether carboxylate (Cl-PFPECA) and legacy perfluorocarboxylate PFAS in native vegetation and subsoil samples collected in New Jersey by New Jersey state government personnel. Samples were originally processed and extracted in Athens, GA EPA/ORD/NERL/EMMD laboratory by Tom Jenkins and John Washington. Samples were analyzed for PFAS on the Waters LC-MS/MS instruments in Athens, GA EPA/ORD/CEMM/EPD laboratory by Mary Davis, Marina Evich, and John Washington. Instrument output was reviewed and optimized by Mary Davis, Marina Evich, and John Washington. This dataset is associated with the following publication: Davis, M., M. Evich, S. Goodrow, and J. Washington. Environmental Fate of Cl-PFPECAs: Accumulation of Novel and Legacy Perfluoroalkyl Compounds in Real-World Vegetation and Subsoils. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 57(24): 8994–9004, (2023).

This file contains data from accumulation of chloro perfluoro polyether carboxylate (Cl-PFPECA) and legacy perfluorocarboxylate PFAS in native vegetation and subsoil samples collected in New Jersey by New Jersey state government personnel. Samples were originally processed and extracted in Athens, GA EPA/ORD/NERL/EMMD laboratory by Tom Jenkins and John Washington. Samples were analyzed for PFAS on the Waters LC-MS/MS instruments in Athens, GA EPA/ORD/CEMM/EPD laboratory by Mary Davis, Marina Evich, and John Washington. Instrument output was reviewed and optimized by Mary Davis, Marina Evich, and John Washington. This dataset is associated with the following publication: Davis, M., M. Evich, S. Goodrow, and J. Washington. Environmental Fate of Cl-PFPECAs: Accumulation of Novel and Legacy Perfluoroalkyl Compounds in Real-World Vegetation and Subsoils. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 57(24): 8994–9004, (2023).

These data were part of a critical review that looks at the occurrence of PFOS in ambient surface waters across the U.S. All data from this paper were obtained from publicly available literature, including peer-review journal articles, theses, and government and industry reports through 2020. These data include measured PFOS concentrations across the U.S., sample site location (i.e., state, waterbody, and GPS coordinates), and dates of sample collection and analysis, and analytical methods used. Citation information for this dataset can be found in the EDG's Metadata Reference Information section and Data.gov's References section.

These data were part of a critical review that looks at the occurrence of PFOS in ambient surface waters across the U.S. All data from this paper were obtained from publicly available literature, including peer-review journal articles, theses, and government and industry reports through 2020. These data include measured PFOS concentrations across the U.S., sample site location (i.e., state, waterbody, and GPS coordinates), and dates of sample collection and analysis, and analytical methods used. Citation information for this dataset can be found in the EDG's Metadata Reference Information section and Data.gov's References section.

Dataset for A Comparison of In Vitro Points of Departure with Human Biomonitoring Levels for Per- and Polyfluoroalkyl Substances (PFAS), to be published by Environmental Health Perspectives (EHP). This dataset is associated with the following publication: Judson, R., D. Smith, M. Devito, J. Wambaugh, B. Wetmore, K. Friedman, G. Patlewicz, R. Thomas, R. Sayre, J. Olker, S. Degitz, S. Padilla, J. Harrill, T. Shafer, and K. Carstens. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS) (Toxics). Toxics. MDPI, Basel, SWITZERLAND, 12(4): 271, (2024).

Data set contains summary data (mean, standard error, sample size) for all measured endpoints from all experiments reported in the published manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, A. Dixon, D. Jenkins-Hill, J. McCord, M. Strynar, J. Ford, and L. Gray. Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, (107631): 1, (2022).

Data set contains summary data (mean, standard error, sample size) for all measured endpoints from all experiments reported in the published manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, A. Dixon, D. Jenkins-Hill, J. McCord, M. Strynar, J. Ford, and L. Gray. Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, (107631): 1, (2022).

A list of structures (and other identifiers) of possible per- and polyfluoroalkyl substances (PFAS). The data provided in the PFAS Suspect List has been aggregated from public sources and users, including peer-reviewed literature, patent literature, and public websites. Therefore, the quality and accuracy of the compound names, structures, and other properties have not been validated. The National Institute of Standards & Technology does not endorse or provide any assessment of confidence with the information provided.