Differences in various mitochondrial bioenergetics parameters in different brain regions in different age groups. This dataset is associated with the following publication: Pandya, J.D., J. Royland , R.C. McPhail, P.G. Sullivan, and P. Kodavanti. Age-and Brain Region-Specific Differences in Mitochondrial Bioenergetics in Brown Norway Rats. NEUROBIOLOGY OF AGING. Elsevier Science Ltd, New York, NY, USA, 42: 25-34, (2016).

This dataset was utilized to evaluate associations between accelerated epigenetic and transcriptomic age and NMR-measured metabolic and inflammatory biomarkers. It contains information on biological and chronological age, confounders, and NMR-measured 'omic profiles. This dataset is not publicly accessible because: The data is derived from medical records which cannot be disclosed per federal law (HIPPA) and existing data use agreements. It can be accessed through the following means: The data can be accessed via sending a request to the CATHGEN Executive Committee (https://dmpi.duke.edu/studies/cathgen). An approved IRB application may be required by the committee. Format: The data is tabular data containing columns specifying the epigenetic and transcriptomic age of the individuals along with NMR-measured metabolic biomarkers. Social and demographic confounders are are included within the dataset. This dataset is associated with the following publication: Raab, H., E. Hauser, L. Kwee, S. Shah, W. Kraus, and C. Ward-Caviness. Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients. Aging. Impact Journals, LLC, Orchard Park, NY, USA, 16(8): 6652-6672, (2024).

Gene array data files compared gene expression profiles in liver samples from young (21-45 years) and old (69+ years) men and women to determine changes in the expression of xenobiotic metabolism enzymes and transporters. We identified genes that were differentially expressed in males only, females only, or in all individuals between the young and old using microarray. This dataset is associated with the following publication: Corton, J., J. Lee, J. Liu, H. Ren, B. Vallanat, and M. Devito. Determinants of Gene Expression in the Human Liver: Impact of Aging and Sex on Xenobiotic Metabolism. Experimental Gerontology. Elsevier Science Ltd, New York, NY, USA, 169: 111976, (2022).

The Physiological Parameters Database for Older Adults is available for download and contains physiological parameters values for healthy older human adults (age 60 and older), as well as data for some individuals with adverse health conditions that may relate to environmental exposure. The information in this database was collected from review of peer-review published papers.

The Physiological Parameters Database for Older Adults is available for download and contains physiological parameters values for healthy older human adults (age 60 and older), as well as data for some individuals with adverse health conditions that may relate to environmental exposure. The information in this database was collected from review of peer-review published papers.

Data corresponding to the figures in this article. This dataset is associated with the following publication: Corteselli, E., J. Samet, and E. Gibbs-Flournoy. IMAGING APPROACHES TO ASSESSMENTS OF TOXICOLOGICAL OXIDATIVE STRESS USING GENETICALLY ENCODED FLUOROGENIC SENSORS. Journal of Visualized Experiments. JoVE, Somerville, MA, USA, 132: 56945, (2018).

The raw values used to create figures 1 and 2 and table 3. This dataset is associated with the following publication: Liu, J., Y. Lu, C. Corton, and C. Klaassen. Expression of cytochrome P450 isozyme transcripts and activities in human livers. XENOBIOTICA. Taylor & Francis, Inc., Philadelphia, PA, USA, 51(3): 279-286, (2021).

Raw data for all figures and tables in manuscript for study analyzing the impact of living conditions on cardiovascular function in ApoE -/- mice. This dataset is associated with the following publication: Fiamingo, M., S. Toler, K. Lee, W. Oshiro, Q. Krantz, P. Evansky, D. Davies, M. Gilmour, A. Farraj, and M. Hazari. Depleted housing elicits cardiopulmonary dysfunction after a single flaming eucalyptus wildfire smoke exposure in a sex-specific manner in ApoE knockout mice.. Cardiovascular Toxicology. Humana Press Incorporated, Totowa, NJ, USA, 24: 852-869, (2024).

This dataset contains ambient air pollution data during the study period and lung function and biomarkers data. This dataset is associated with the following publication: Tong, H., S. Zhang, W. Shen, H. Chen, C. Salazar, A. Schneider, A. Rappold, D. Diaz-Sanchez, R. Devlin, and J. Samet. Lung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids. Annals of the American Thoracic Society. American Thoracic Society, New York, NY, USA, 19(4): 583-593, (2022).