Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from over 1,000 public sources on over 500,000 chemicals and is searchable by chemical name, other identifiers and by chemical structure. It can be used to query a specific chemical and find all publicly available hazard, exposure and risk assessment data. It also provides access to EPA's ToxCast, ToxRefDB, DSSTox, Dashboard and DSSTox data.

The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data. It helps to build a data foundation for improved structure-activity relationships and predictive toxicology. DSSTox publishes summarized chemical activity representations for structure-activity modeling and provides a structure browser. This tool also houses the chemical inventories for the ToxCast and Tox21 projects.

EPA researchers have been using advances in computational toxicology to address lack of data on the thousands of chemicals. EPA released chemical data on 1,800 chemicals. The 1,800 chemicals were screened in more than 800 rapid, automated tests (called high-throughput screening assays) to determine potential human health effects. The data is available through the interactive Chemical Safety for Sustainability Dashboards (iCSS dashboard) and the complete data sets are also available for download.

EPA researchers have been using advances in computational toxicology to address lack of data on the thousands of chemicals. EPA released chemical data on 1,800 chemicals. The 1,800 chemicals were screened in more than 800 rapid, automated tests (called high-throughput screening assays) to determine potential human health effects. The data is available through the interactive Chemical Safety for Sustainability Dashboards (iCSS dashboard) and the complete data sets are also available for download.

The Exposure Forecaster Database (ExpoCastDB) is EPA's database for aggregating chemical exposure information and can be used to help with chemical exposure predictions. The database currently includes biomonitoring exposure data from three studies: the American Healthy Homes Survey, the First National Environmental Health Survey of Child Care Centers and the Children's Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants study. Data include the amounts of chemicals found in food, drinking water, air, dust indoor surfaces and urine. The database will eventually include high-throughput exposure predictions for thousands of chemicals based on manufacture and use information. EPA researchers developed high-throughput exposure models to predict exposures for 1,763 chemicals using production volume, environmental fate and transport models, and a simple indicator of consumer product use.The model is being improved by adding more refined indoor and consumer use information since these are also large determinants of exposure. As these models are refined and more exposure data is collected, it will be added to ExpoCastDB.

The Exposure Forecaster Database (ExpoCastDB) is EPA's database for aggregating chemical exposure information and can be used to help with chemical exposure predictions. The database currently includes biomonitoring exposure data from three studies: the American Healthy Homes Survey, the First National Environmental Health Survey of Child Care Centers and the Children's Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants study. Data include the amounts of chemicals found in food, drinking water, air, dust indoor surfaces and urine. The database will eventually include high-throughput exposure predictions for thousands of chemicals based on manufacture and use information. EPA researchers developed high-throughput exposure models to predict exposures for 1,763 chemicals using production volume, environmental fate and transport models, and a simple indicator of consumer product use.The model is being improved by adding more refined indoor and consumer use information since these are also large determinants of exposure. As these models are refined and more exposure data is collected, it will be added to ExpoCastDB.

The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the Dashboard has been aggregated over the past 15 years by both manual and auto-curation techniques within EPA’s DSSTox project.These data include physicochemical, environmental fate and transport, exposure, usage, in vivo toxicity, and in vitro bioassay data, surfaced through an integration hub with link-outs to additional EPA data and public domain online resources. This dataset is associated with the following publication: Williams, A., C. Grulke, J. Edwards, A. McEachran, K. Mansouri, N. Baker, G. Patlewicz, I. Shah, J. Wambaugh, R. Judson, and A. Richard. (Journal of Cheminformatics) The CompTox Chemistry Dashboard - A Community Data Resource for Environmental Chemistry. Journal of Cheminformatics. Springer, New York, NY, USA, 9(61): 1-27, (2017).

The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the Dashboard has been aggregated over the past 15 years by both manual and auto-curation techniques within EPA’s DSSTox project.These data include physicochemical, environmental fate and transport, exposure, usage, in vivo toxicity, and in vitro bioassay data, surfaced through an integration hub with link-outs to additional EPA data and public domain online resources. This dataset is associated with the following publication: Williams, A., C. Grulke, J. Edwards, A. McEachran, K. Mansouri, N. Baker, G. Patlewicz, I. Shah, J. Wambaugh, R. Judson, and A. Richard. (Journal of Cheminformatics) The CompTox Chemistry Dashboard - A Community Data Resource for Environmental Chemistry. Journal of Cheminformatics. Springer, New York, NY, USA, 9(61): 1-27, (2017).

The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use information is compiled from multiple sources while product information is gathered from publicly available Material Safety Data Sheets (MSDS). EPA researchers are evaluating the possibility of expanding the database with additional product and use information.

The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use information is compiled from multiple sources while product information is gathered from publicly available Material Safety Data Sheets (MSDS). EPA researchers are evaluating the possibility of expanding the database with additional product and use information.