This work contributes to an understanding of the hydrologic cycle of the State of Alaska and the part of the Canadian Yukon Territory draining into Alaska. For purposes of this study, the domain is simply referred to as “Alaska (AK)". This data release contains inputs for and outputs from hydrologic simulations for the Alaska (AK) domain using the Precipitation Runoff Modeling System (PRMS) version 5.2.1.1 for the precalibration and byHRU (by Hydrologic Response Unit) release using the USGS National Hydrologic Model infrastructure (NHM; Regan and others, 2018). These simulations were developed to provide estimates of the water budget for the calendar-year period 1980 to2021. Specific file types include: 1) monthly calibration target baselines derived from Global Circulation Model (GCM) simulations (Koczot and others, 2025), 2) map of permanent snow during January 1980 - October 2022 and resulting parameter values of initial snowpack depths, 3) input atmospheric forcings of minimum air temperature, maximum air temperature, and daily precipitation accumulation derived from Daymet Version 4 gridded estimates of daily weather parameters (Thornton and others, 2020) and input parameter and control files for each release (Bock and others, 2024; Markstrom and others, 2015), 4) output files of simulated water budget components for each hydrologic response unit and stream segment and 5) performance statistics at selected streamgage locations. Figure 1 (Rosa and others, 2024) shows the calibration methodology that was used for the model application (see Hay and others, 2023 for additional information). Figure 2 (Bock and others, 2024) shows all the HRUs in the geospatial fabric for the AK domain. Table 1 (Table_1_AK_gages.csv) lists the streamgages that are included in the model application. Of the total 287 in this set, 250 will be used as calibration targets in the third and final calibration step (not included in the first publication of this data release). The first three years of the simulations are considered 'model initialization' and should not be included in any subsequent analysis. The executable used for these simulations may be downloaded from https://www.usgs.gov/software/precipitation-runoff-modeling-system-prms (version 5.2.1.1). A batch files to run the model configurations has also been included. CONTENTS OF THIS PARENT PAGE: 1. Figure 1.png = Schematic of calibration procedure. 2. Figure 2.png = Map of Hydrologic Response Units (HRUs). 3. Table_1_AK_gages.csv = List of Alaska and Yukon streamflow gages used in this study. 4. control_data_dictionary.csv = Control File parameter and variable definitions. 5. AK_output_variables_data_dictionary.csv = Output variables definitions. 6. parameters_data_dictionary.csv = Parameter definitions. 7. AK_simulated_streamflow_data_dictionary.csv = Streamflow-specific variable definitions. See Child Items.