These data are from a human study collected under IRB protocol: ClinicalTrials.gov # NCT01874834. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: These data are from a human study collected under IRB protocol: ClinicalTrials.gov # NCT01874834. As such, it is a violation of Federal Law to publish them. Format: These data are from a human study collected under IRB protocol: ClinicalTrials.gov # NCT01874834. This dataset is associated with the following publication: Stiegel, M., J. Pleil, J. Sobus, T. Stevens, and M. Madden. Linking physiological parameters to perturbations in the human exposome: Environmental exposures modify blood pressure and lung function via inflammatory cytokine pathway. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, USA, 80(9): 485-501, (2017).

All data are provided within report tables available on the website with appropriate header information. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: Publicly available data used for this evaluation are located at https://cfpub.epa.gov/ncea/risk/ recordisplay.cfm?deid=351563. Additional BHSS details are publicly available at https://cumulis.epa.gov/supercpad/cursites/csitinfo.cfm?id=1000195. Format: The data used for this evaluation were collected during routine BLL monitoring at the Bunker Hill Superfund (BHSS) site by the local Kellogg Idaho Panhandle Health District under the auspices of the Idaho Department of Environmental Quality (IDEQ). IDEQ contracts with Alta Science and Engineering, Inc. for technical, scientific, and engineering services at the BHSS, including maintaining the blood Pb and environmental databases. Alta maintains these data in a confidential (coded) format that prevents the identification of the participants and their home locations. With permission of IDEQ, Alta staff used paired BHSS BLL and environmental media concentration data to evaluate the IEUBK model v2.0. Transfer of individual or confidential data from Alta to SRC and EPA was expressly prohibited. This dataset is associated with the following publication: Brown, J. Evaluation of IEUBK journal article. Journal of Exposure Science and Environmental Epidemiology. Nature Publishing Group, London, UK, 36123530, (2022).

All data are provided within report tables available on the website with appropriate header information. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: Publicly available data used for this evaluation are located at https://cfpub.epa.gov/ncea/risk/ recordisplay.cfm?deid=351563. Additional BHSS details are publicly available at https://cumulis.epa.gov/supercpad/cursites/csitinfo.cfm?id=1000195. Format: The data used for this evaluation were collected during routine BLL monitoring at the Bunker Hill Superfund (BHSS) site by the local Kellogg Idaho Panhandle Health District under the auspices of the Idaho Department of Environmental Quality (IDEQ). IDEQ contracts with Alta Science and Engineering, Inc. for technical, scientific, and engineering services at the BHSS, including maintaining the blood Pb and environmental databases. Alta maintains these data in a confidential (coded) format that prevents the identification of the participants and their home locations. With permission of IDEQ, Alta staff used paired BHSS BLL and environmental media concentration data to evaluate the IEUBK model v2.0. Transfer of individual or confidential data from Alta to SRC and EPA was expressly prohibited. This dataset is associated with the following publication: Brown, J. Evaluation of IEUBK journal article. Journal of Exposure Science and Environmental Epidemiology. Nature Publishing Group, London, UK, 36123530, (2022).

This SAS dataset contains data on salivary concentrations of selected immune and neuroendocrine biomarkers, as well as socioeconomic and demographic data, self-reported health data, and behavioral data. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: This dataset is available upon request. Eligible researchers can contact study investigators Andrey Egorov (egorov.andrey@epa.gov) or Michael Nye (nye.michale@epa.gov). Format: This dataset contains demographic, socioeconomic, behavioral and stress data on residents of two communities in Denver, CO, as well as data on biomarker levels in saliva. This dataset is associated with the following publication: Egorov, A., W. Xue, J. Kobylanski, M. Fuzawa, S. Griffin, T. Wade, and M. Nye. Pilot application of an inflammation and physiological dysregulation index based on noninvasive salivary biomarkers. BMC Research Notes. BioMed Central Ltd, London, UK, 18: 53, (2025).

Emory University (analyzed the urine samples for pyrethroid metabolites). This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: Contact Researcher. Format: Pyrethroid metabolite concentration data for 50 adults over six-weeks. This dataset is associated with the following publication: Morgan , M., J. Sobus , D.B. Barr, C. Croghan , F. Chen , R. Walker, L. Alston, E. Andersen, and M. Clifton. Temporal variability of pyrethroid metabolite levels in bedtime, morning, and 24-hr urine samples for 50 adults in North Carolina. ENVIRONMENT INTERNATIONAL. Elsevier Science Ltd, New York, NY, USA, 144: 81-91, (2015).

Emory University (analyzed the urine samples for pyrethroid metabolites). This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: Contact Researcher. Format: Pyrethroid metabolite concentration data for 50 adults over six-weeks. This dataset is associated with the following publication: Morgan , M., J. Sobus , D.B. Barr, C. Croghan , F. Chen , R. Walker, L. Alston, E. Andersen, and M. Clifton. Temporal variability of pyrethroid metabolite levels in bedtime, morning, and 24-hr urine samples for 50 adults in North Carolina. ENVIRONMENT INTERNATIONAL. Elsevier Science Ltd, New York, NY, USA, 144: 81-91, (2015).

Annual mortality rates for US counties, air pollution concentrations. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: Please contact corresponding author. Format: Data is saved in Ascii and netcdf format. This dataset is associated with the following publication: Peterson, G., C. Hogrefe, L. Neas, A. Corrigan, R. Mathur, and A. Rappold. Impacts of Reductions in Emissions from Major Source Sectors on Fine Particulate Matter-Related Cardiovascular Mortality. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 128(1): 17005, (2020).

Annual mortality rates for US counties, air pollution concentrations. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: Please contact corresponding author. Format: Data is saved in Ascii and netcdf format. This dataset is associated with the following publication: Peterson, G., C. Hogrefe, L. Neas, A. Corrigan, R. Mathur, and A. Rappold. Impacts of Reductions in Emissions from Major Source Sectors on Fine Particulate Matter-Related Cardiovascular Mortality. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 128(1): 17005, (2020).

This dataset contains a summary of compounds found in human urine samples. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: The original dataset contains identification information for the sample subjects and all of their descriptors including age, gender, race, and medical screening information. The analyzed data cannot be made publicly available. Format: This dataset contains a summary of compounds found in human urine samples. This dataset is associated with the following publication: O’Lenick, C., J. Pleil, M. Stiegel, J. Sobus, and A. Wallace. Detection and analysis of endogenous polar volatile organic compounds (PVOCs) in urine for human exposome research. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, USA, 24(3): 240-248, (2019).

This dataset contains a summary of compounds found in human urine samples. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: The original dataset contains identification information for the sample subjects and all of their descriptors including age, gender, race, and medical screening information. The analyzed data cannot be made publicly available. Format: This dataset contains a summary of compounds found in human urine samples. This dataset is associated with the following publication: O’Lenick, C., J. Pleil, M. Stiegel, J. Sobus, and A. Wallace. Detection and analysis of endogenous polar volatile organic compounds (PVOCs) in urine for human exposome research. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, USA, 24(3): 240-248, (2019).