This dataset is a hydrographic survey collected by sensors mounted on gliders in the Weddell Sea sector of the Antarctic Marginal Ice Zone, as part of the Robotic Observations and Modeling of the Marginal Ice Zone (ROAMMIZ) project. The gliders, SG643 (Caltech) and SG640 (Gothenburg University), were deployed from the research vessel SA AGULHAS II in the austral summer of 2018 and spring of 2019, respectively. Each of the profiles provide temperature, salinity, dissolved oxygen, fluorescence, optical backscatter (at 470 and 700 nm) and Depth Averaged Currents. The deployment in 2018 also includes PAR. Data were measured to a depth of 1000 m except for fluorescence and backscatter which recorded to a depth of 400 m. Horizontal resolution ranges from 300 m to 5000 m as a result of the V-shaped sampling pattern characteristic of gliders. The concatenated files provide processed and calibrated temperature, salinity, chlorophyll and backscatter data using near-by CTD casts on deployment and recovery of the gliders. The individual profiles have been processed on the Kongsberg basestation and the thermal lag correction of Charlie Erickson (unpublished) applied, but the data is otherwise not post-calibrated. The raw data of SG643 is also provided in case the user would like to re-process the data. Otherwise, the data are in NetCDF. Data were collected with support from ROAMMIZ Project; Terrestrial Hazard Observations and Reporting (THOR) Center and Linde Center at Caltech ; Packard Foundation.