데이터셋 상세
미국
Data submission for A-d25f
Includes 1) list of genes in the STAT5b biomarker and 2) list of accession numbers for microarray datasets used in study. This dataset is associated with the following publication: Oshida, K., N. Vasani, D. Waxman, and C. Corton. Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event. PLoS ONE. Public Library of Science, San Francisco, CA, USA, 11(3): NA, (2016).
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연관 데이터
Data submission for A-d25f
공공데이터포털
Includes 1) list of genes in the STAT5b biomarker and 2) list of accession numbers for microarray datasets used in study. This dataset is associated with the following publication: Oshida, K., N. Vasani, D. Waxman, and C. Corton. Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event. PLoS ONE. Public Library of Science, San Francisco, CA, USA, 11(3): NA, (2016).
Datasets in Gene Expression Omnibus used in the study ORD-020969: Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice
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Datasets in Gene Expression Omnibus used in the study ORD-020969: Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice. This dataset is associated with the following publication: Rooney, J., N. Ryan, B. Chorley, S. Hester, E. Kenyon, J. Schmid, B. George, M. Hughes, Y. Sey, A. Tennant, D. MacMillan, J. Simmons, C. McQueen, A. Pandiri, C. Wood, and C. Corton. Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice. TOXICOLOGICAL SCIENCES. Society of Toxicology, 160(1): 15–29, (2017).
Data submission for A-0k6f
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List of biomarker genes used to predict estrogen receptor activity in MCF-7 cells; list of microarray accession numbers used in the study. This dataset is associated with the following publication: Vanduyn, N., B. Chorley , R. Tice, R. Judson , and C. Corton. Moving Toward Integrating Gene Expression Profiling into High-throughput Testing:A Gene Expression Biomarker Accurately Predicts Estrogen Receptor α Modulation in a Microarray Compendium. TOXICOLOGICAL SCIENCES. Society of Toxicology, 151(1): 88-103, (2016).
Supporting data for Suen et al A-0zpd
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Tables, Figures, and Supplemental Materials for doi: 10.1158/1541-7786.MCR-16-0084. This dataset is associated with the following publication: Suen, A., W. Jefferson, C. Wood, E. Padilla-Banks, V. Bae-Jump, and C. Williams. SIX1 Oncoprotein as a Biomarker in a Model of Hormonal Carcinogenesis and in Human Endometrial Cancer.. Molecular Cancer Research. American Association for Cancer Research, Inc., Philadelphia, PA, USA, 14(9): 849-858, (2016).
Datasets used in ORD-023417: Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium
공공데이터포털
Datasets used in ORD-023417: Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium. This dataset is associated with the following publication: Rooney, J., B. Chorley, N. Kleinstreuer, and C. Corton. Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 166(1): 146-162, (2018).
Datasets for Figures and Tables in SIX1 regulates aberrant endometrial epithelial cell differentiation and cancer trajectory
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Data associated with the figures presented in this study are images, graphics, or tabulated data based on histopathologic analysis performed by a certified study pathologist or image analysis. Data for Tables 1 and 2 provide incidence, labeling scores, and p-values for statistical tests for uterine pathology and IHC expression by treatment group and timepoint or human endometrial tissue, as described in the Main Text file of the manuscript. Manual histopathologic data can be found in excel spreadsheets and are based on presence/absences (yes/no) of a pathologic finding and/or severity score as described in the manuscript (Fig. 1, 2, 3, 4). The image analysis data is based on the quantified area that is designated as “positive” for a particular immunohistochemical stain (Fig. 2, 4, and Suppl. Fig. S2). Supplementary Table 1 provides summary information on antibodies used for immunohistochemistry. Supplementary fig. S1 includes real time RT-PCR data standardized to a housekeeping gene and western blot data. This dataset is associated with the following publication: Suen, A., W. Jefferson, C. Wood, and C. Williams. SIX1 regulates aberrant endometrial epithelial cell differentiation and cancer trajectory. Molecular Cancer Research. American Association for Cancer Research, Inc., Philadelphia, PA, USA, 17(12): 2369-2382, (2019).
Datasets for Figures and Tables in SIX1 regulates aberrant endometrial epithelial cell differentiation and cancer trajectory
공공데이터포털
Data associated with the figures presented in this study are images, graphics, or tabulated data based on histopathologic analysis performed by a certified study pathologist or image analysis. Data for Tables 1 and 2 provide incidence, labeling scores, and p-values for statistical tests for uterine pathology and IHC expression by treatment group and timepoint or human endometrial tissue, as described in the Main Text file of the manuscript. Manual histopathologic data can be found in excel spreadsheets and are based on presence/absences (yes/no) of a pathologic finding and/or severity score as described in the manuscript (Fig. 1, 2, 3, 4). The image analysis data is based on the quantified area that is designated as “positive” for a particular immunohistochemical stain (Fig. 2, 4, and Suppl. Fig. S2). Supplementary Table 1 provides summary information on antibodies used for immunohistochemistry. Supplementary fig. S1 includes real time RT-PCR data standardized to a housekeeping gene and western blot data. This dataset is associated with the following publication: Suen, A., W. Jefferson, C. Wood, and C. Williams. SIX1 regulates aberrant endometrial epithelial cell differentiation and cancer trajectory. Molecular Cancer Research. American Association for Cancer Research, Inc., Philadelphia, PA, USA, 17(12): 2369-2382, (2019).
IN VITRO AND IN VIVO ANDROGEN RECEPTOR DATA SET FROM TOX SCI PAPER GRAY ET AL 2020
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Data sets include 1. Excel file with Hershberger assay protocols and data and summaries of in vivo antiandrogen studies 2. Figures of in vitro AR assay results from contract work and in house studies 3. Excel file with in house in vitro AR antagonism data. This dataset is associated with the following publication: Gray, L., J. Furr, C. Lambright, N. Evans, P. Hartig, M. Cardon, V. Wilson, A. Hotchkiss, and J. Conley. Quantification of uncertainties in extrapolating from in vitro androgen receptor (AR) antagonism to in vivo Hershberger Assay endpoints and adverse reproductive development in male rats. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 176(2): 297-311, (2020).
IN VITRO AND IN VIVO ANDROGEN RECEPTOR DATA SET FROM TOX SCI PAPER GRAY ET AL 2020
공공데이터포털
Data sets include 1. Excel file with Hershberger assay protocols and data and summaries of in vivo antiandrogen studies 2. Figures of in vitro AR assay results from contract work and in house studies 3. Excel file with in house in vitro AR antagonism data. This dataset is associated with the following publication: Gray, L., J. Furr, C. Lambright, N. Evans, P. Hartig, M. Cardon, V. Wilson, A. Hotchkiss, and J. Conley. Quantification of uncertainties in extrapolating from in vitro androgen receptor (AR) antagonism to in vivo Hershberger Assay endpoints and adverse reproductive development in male rats. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 176(2): 297-311, (2020).
Datasets in Gene Expression Omnibus used in the study ORD-020382: Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents
공공데이터포털
GEO accession number of the microarray study. This dataset is associated with the following publication: Mesnage, R., A. Phedonos, M. Biserni, M. Arno, S. Balu, C. Corton, R. Ugarte, and M. Antoniou. Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 108: 30-42, (2017).