Data submission for A-p8dg
공공데이터포털
Accession numbers for microarray datasets used in Oshida et al. Chemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver Transcriptome. PLoS One. 2016 Mar 9;11(3):e0150284. This dataset is associated with the following publication: Oshida, K., D. Waxman, and C. Corton. Chemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver Transcriptome.. PLoS ONE. Public Library of Science, San Francisco, CA, USA, 11(3): NA, (2016).
Data submission for A-gf27
공공데이터포털
Biomarker genes used to predict AhR activity; accession numbers of microarray datasets used in the study. This dataset is associated with the following publication: Oshida, K., N. Vasani, W. Ward , R. Thomas , D. Applegate, F. Gonzalez, L. Aleksunes, C. Klaassen, and C. Corton. Screening a mouse liver gene expression Compendium Identifies Effectors of the Aryl Hydrocarbon reeptors (AhR). TOXICOLOGICAL SCIENCES. Society of Toxicology, 336: 99-112, (2015).
PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling
공공데이터포털
Microarray datasets used in the analysis. This dataset is associated with the following publication: Rosen, M., K. Das, J. Rooney, B. Abbott, C. Lau, and C. Corton. PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 387: 95-107, (2017).
PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling
공공데이터포털
Microarray datasets used in the analysis. This dataset is associated with the following publication: Rosen, M., K. Das, J. Rooney, B. Abbott, C. Lau, and C. Corton. PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 387: 95-107, (2017).
Datasets in Gene Expression Omnibus used in the study ORD-022075: Chemical Activation of the Constitutive Activated Receptor (CAR) Leads to Activation of Oxidant-Induced Nrf2
공공데이터포털
Gene Expression Omnibus (GEO) accession numbers of studies used in the analysis. This dataset is associated with the following publication: Rooney, J., K. Oshida, R. Kumar, W. Baldwin, and C. Corton. Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(1): 172-189, (2019).
Datasets in Gene Expression Omnibus used in the study ORD-022075: Chemical Activation of the Constitutive Activated Receptor (CAR) Leads to Activation of Oxidant-Induced Nrf2
공공데이터포털
Gene Expression Omnibus (GEO) accession numbers of studies used in the analysis. This dataset is associated with the following publication: Rooney, J., K. Oshida, R. Kumar, W. Baldwin, and C. Corton. Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(1): 172-189, (2019).
Liver steatosis study PFAA treated mouse gene array data
공공데이터포털
This file contains a link for Gene Expression Omnibus and the GSE designations for the publicly available gene expression data used in the study and reflected in Figures 6 and 7 for the Das et al., 2016 paper. This dataset is associated with the following publication: Das, K., C. Wood, M. Lin, A.A. Starkov, C. Lau, K.B. Wallace, C. Corton, and B. Abbott. Perfluoroalky acids-induced liver steatosis: Effects on genes controlling lipid homeostasis. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 378: 32-52, (2017).
Liver steatosis study PFAA treated mouse gene array data
공공데이터포털
This file contains a link for Gene Expression Omnibus and the GSE designations for the publicly available gene expression data used in the study and reflected in Figures 6 and 7 for the Das et al., 2016 paper. This dataset is associated with the following publication: Das, K., C. Wood, M. Lin, A.A. Starkov, C. Lau, K.B. Wallace, C. Corton, and B. Abbott. Perfluoroalky acids-induced liver steatosis: Effects on genes controlling lipid homeostasis. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 378: 32-52, (2017).
Datasets in Gene Expression Omnibus used in the study ORD-020969: Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice
공공데이터포털
Datasets in Gene Expression Omnibus used in the study ORD-020969: Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice. This dataset is associated with the following publication: Rooney, J., N. Ryan, B. Chorley, S. Hester, E. Kenyon, J. Schmid, B. George, M. Hughes, Y. Sey, A. Tennant, D. MacMillan, J. Simmons, C. McQueen, A. Pandiri, C. Wood, and C. Corton. Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice. TOXICOLOGICAL SCIENCES. Society of Toxicology, 160(1): 15–29, (2017).
Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic proteomic and epigenomic data
공공데이터포털
RR-1 is a validation flight to evaluate the hardware operational and science capabilities of the Rodent Research Project on the ISS. RNA DNA and protein were purified from liver tissues from RR-1 mice (female C57Bl6/J 16wk old at time of launch) including eight from the Flight group and eight from the Ground Control group. From each group two liver samples were collected and frozen immediately after euthanasia (Flight mice dissected on-orbit after total 37 days after launch Samples FLT-M21 M22 and corresponding Ground Control samples GC-M31,M32). An additional six samples from each group were collected from frozen carcasses dissected post-flight (Samples FLT-M25,M26,M27,M28,M29,M30 and corresponding Ground Control samples GC-M35,M36,M37,M38,M39,M40). RNA-Seq whole genome and RNA BS-Seq (bisulfite sequencing) and proteomic expression profiling were performed.