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Effects of Simulated Smog in Rodent Models of Disease Dataset.
The dataset includes the draft main paper and supporting information file to be submitted to the journal, and also excel spread sheets containing the raw data which backs up the processed data used in the paper and supporting information file. Data include exposure characterization (temperature, RH, pollutant levels, etc.), physiology data, serum data, lung inflammation data, viral burden data, PCR data, blood data, lung pathology data, and other miscellaneous data. All the column headings and other relevant definitions and information are included in the data sets, and match the relevant data in the paper to be submitted. This dataset is associated with the following publication: Hargrove, M., S. Snow, R. Luebke, C. Wood, J. Krug, T. Krantz, C. King, C. Copeland, S. McCullough, K. Gowdy, U. Kodavanti, I. Gilmour, and S. Gavett. Effects of Simulated Smog Atmospheres in Rodent Models of Metabolic and Immunologic Dysfunction. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 52(5): 3062-3070, (2018).
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Tong EPA smog manuscript dataset
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cardiovascular responses of exposure to simulated smog atmospheres in animals. This dataset is associated with the following publication: Tong, H., J. Krug, T. Krantz, C. King, M. Hargrove, I. Gilmour, and S. Gavett. Inhalation of Simulated Smog Atmospheres Affects Cardiac Function in Mice#. Cardiovascular Toxicology. Humana Press Incorporated, Totowa, NJ, USA, 18(6): 569-578, (2019).
Respiratory Effects and Systemic Stress Response Following Acute Acrolein Inhalation in Rats
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This data set is an Excel file pertaining to the study that examined nasal, pulmonary, and systemic effects of acrolein in rats acutely exposed to a range of concentrations. The different tabs of the spreadsheet pertain to each figure found in the manuscript. This dataset is associated with the following publication: Snow, S., M. McGee, A. Henriquez, J. Richards, M. Schladweiler, A. Ledbetter, and U. Kodavanti. Respiratory Effects and Systemic Stress Response Following Acute Acrolein Inhalation in Rats#. TOXICOLOGICAL SCIENCES. Society of Toxicology, 158(2): 454-464, (2017).
Dataset: Smoldering and Flaming Biomass Wood Smoke Inhibit Respiratory Responses in Mice
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The dataset consists of 2 revised files. The excel file shows all of the individual data used in calculation of the tables and figures. Each table and figure has data stored on a separate tab of the file. The zip file consists of 5 GraphPad Prism files which show the statistics and graphs used in the paper. The names of the 5 files indicate which figures and tables are analyzed statistically and the graphs generated from the data. This dataset is associated with the following publication: Hargrove, M., Y.H. Kim, C. King, C. Wood, M. Gilmour, J. Dye, and S. Gavett. Smoldering and Flaming Biomass Wood Smoke Inhibit Respiratory Responses in Mice. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 31(6): 236-247, (2019).
Ozone-induced systemic and pulmonary effects are diminished in adrenalectomized rats
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This data set is an excel file pertaining to the study that examined ozone-induced systemic and pulmonary effects in rats that underwent SHAM surgery (control), adrenal demedullation or total bilateral adrenalectomy. Different pages of the spreadsheet shows individual animal data for markers of lung injury and inflammation, body weights, whole body plethysmography measurements, levels of circulating hormones and lipids, and circulating white blood cell count as well as platelet count. This dataset is associated with the following publication: Miller, D., S. Snow, M. Schladweiler , J. Richards , A. Ghio , A. Ledbetter , and U. Kodavanti. Acute Ozone-Induced Pulmonary and Systemic Metabolic Effects are Diminished in Adrenalectomized Rats#. TOXICOLOGICAL SCIENCES. Society of Toxicology, 150(2): 312-22, (2016).
Excel spreadsheet of data used in Figure 3
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Distribution of doses of a volatile organic compound from inhalation of one consumer product, other near -field sources, far-field sources, and aggregate (total) exposure. In this instance, far-field scenarios account for several orders of magnitude of less of the predicted dose compared to near-field scenarios. This dataset is associated with the following publication: Vallero, D. Air Pollution Monitoring Changes to Accompany the Transition from a Control to a Systems Focus. Sustainability. MDPI AG, Basel, SWITZERLAND, 8(12): 1216, (2016).
Modeling Rabbit Responses to Single and Multiple Aerosol Exposures of Bacillus anthracis Spores Data Set
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The two excel files contain all of the raw data that was modeled in the R code. The 6 word documents contain all of the R code that can be used in R to model the raw rabbit data. This dataset is associated with the following publication: Bartrand, T., H. Marks, M. Coleman, D. Donahue, S. Hines, J. Comer, and S. Taft. Modeling Rabbit Responses to Single and Multiple Aerosol Exposures of Bacillus anthracis Spores (HS 4.04.02 - 475). RISK ANALYSIS. Blackwell Publishing, Malden, MA, USA, 37(5): 943-957, (2017).
Data sets for manuscript titled Unexpected benefits of reducing aerosol cooling effects
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These data sets were created using extensive model simulation results from the WRF-CMAQ model, population distributions, and through the use of an health impact assessment model - see manuscript for details. This dataset is associated with the following publication: Xing, J., J. Wang, R. Mathur , J. Pleim , S. Wang, C. Hogrefe , C. Gan, D. Wong , and J. Hao. Unexpected Benefits of Reducing Aerosol Cooling Effects. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 50(14): 7527–7534, (2016).
Peat Smoke High Fat All data Feb2018.xlsx
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The data set is an excel spreadsheet containing all the raw data used to generate the tables and figures in the manuscript. This dataset is associated with the following publication: Martin, B., L. Thompson, Y. Kim, W. Williams, S. Snow, M. Schladweiler, P. Phillips, C. King, J. Richards, N. Coates, M. Higuchi, I. Gilmour, U. Kodavanti, M. Hazari, and A. Farraj. Acute Peat Smoke Inhalation Sensitizes Rats to the Postprandial Cardiometabolic Effects of a High Fat Oral Load. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 643: 378-391, (2018).
Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats
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This data set provides the biological endpoints collected from individual animals that culminated into a published paper. This dataset is associated with the following publication: Snow, S., C. Gordon , V. Bass, M. Schladweiler , A. Ledbetter , K. Jarema , P. Phillips , A. Johnstone , and U. Kodavanti. Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats. INHALATION TOXICOLOGY. Informa Healthcare USA, New York, NY, USA, 28(7): 313-23, (2016).
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