This dataset contains toxicity endpoint and mode-of-action information used in an analysis of comparative toxicity and surrogate data approaches to ecological risk assessment of amphibians. Citation information for this dataset can be found in the EDG's Metadata Reference Information section and Data.gov's References section.

The data include concentrations of current use pesticides in tissues of larval wood frog (Lithobates sylvaticus) and spotted salamander (Ambystoma maculatum) and the presence of ranavirus in wood frogs and spotted salamanders from three northeastern National Wildlife Refuges sampled in 2013 and 2014. The data also include estrogenicity, protein phosphatase 2A inhibition and a suite of 15 major and minor elements in sediment screened using portable X-Ray Fluorescence. The data include sediment and tissue samples collected from 16 wetlands at the Patuxent Research Refuge (PRR) in central Maryland, USA, 15 wetlands at the Assabet River and Oxbow National Wildlife Refuges (EMASS) in eastern Massachusetts, USA, and nine wetlands at the Chesapeake and Ohio Canal National Historic Park (CHOH) near the border of Washington DC and Maryland, USA.

The data include concentrations of current use pesticides in tissues of larval wood frog (Lithobates sylvaticus) and spotted salamander (Ambystoma maculatum) and the presence of ranavirus in wood frogs and spotted salamanders from three northeastern National Wildlife Refuges sampled in 2013 and 2014. The data also include estrogenicity, protein phosphatase 2A inhibition and a suite of 15 major and minor elements in sediment screened using portable X-Ray Fluorescence. The data include sediment and tissue samples collected from 16 wetlands at the Patuxent Research Refuge (PRR) in central Maryland, USA, 15 wetlands at the Assabet River and Oxbow National Wildlife Refuges (EMASS) in eastern Massachusetts, USA, and nine wetlands at the Chesapeake and Ohio Canal National Historic Park (CHOH) near the border of Washington DC and Maryland, USA.

Data collected from the metabolomics analysis (GC/MS) of fish and amphibians following exposure to six high use pesticides. The objective of the study was to assess the applicability of using surrogate species data in ecological risk assessments.

Data collected from the metabolomics analysis (GC/MS) of fish and amphibians following exposure to six high use pesticides. The objective of the study was to assess the applicability of using surrogate species data in ecological risk assessments.

GC/MS data from the metabolomic profiling of green frog livers after exposure to pesticides and their mixtures. This dataset is associated with the following publication: Van Meter, R., D. Glinski, T. Purucker, and M. Henderson. Influence of exposure to pesticide mixtures on the metabolomic profile in post-metamorphic green frogs (Lithobates clamitans). SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 624: 1348-1359, (2018).

GC/MS data from the metabolomic profiling of green frog livers after exposure to pesticides and their mixtures. This dataset is associated with the following publication: Van Meter, R., D. Glinski, T. Purucker, and M. Henderson. Influence of exposure to pesticide mixtures on the metabolomic profile in post-metamorphic green frogs (Lithobates clamitans). SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 624: 1348-1359, (2018).

GC/MS metabolomic data from livers of amphibians exposed to pesticides. This dataset is associated with the following publication: Glinski, D., T. Purucker, R. Van Meter, M. Black, and M. Henderson. Endogenous and exogenous biomarker analysis in terrestrial phase amphibians (Lithobates sphenocephala) following dermal exposure to pesticide mixtures. ENVIRONMENTAL CHEMISTRY. CSIRO Publishing, Collingwood Victoria, AUSTRALIA, 16(1): 55-67, (2019).

GC/MS metabolomic data from livers of amphibians exposed to pesticides. This dataset is associated with the following publication: Glinski, D., T. Purucker, R. Van Meter, M. Black, and M. Henderson. Endogenous and exogenous biomarker analysis in terrestrial phase amphibians (Lithobates sphenocephala) following dermal exposure to pesticide mixtures. ENVIRONMENTAL CHEMISTRY. CSIRO Publishing, Collingwood Victoria, AUSTRALIA, 16(1): 55-67, (2019).

Amphibian metabolite data used in Snyder, M.N., Henderson, W.M., Glinski, D.G., Purucker, S. T., 2017. Biomarker analysis of american toad (Anaxyrus americanus) and grey tree frog (Hyla versicolor) tadpoles following exposure to atrazine. Aquatic Toxicology, 182(184-193). doi: 10.1016/j.aquatox.2016.11.018. This dataset is associated with the following publication: Snyder, M., M. Henderson, D. Glinski, and T. Purucker. Biomarker analysis of American toad (Anaxyrus americanus) and grey tree frog (Hyla versicolor) tadpoles following exposure to atrazine.. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 182: 184-193, (2017).