Medical Subject Headings (MeSH) is a hierarchically-organized terminology for indexing and cataloging of biomedical information. It is used for the indexing of PubMed and other NLM databases. Please see the Terms and Conditions for more information regarding the use and re-use of MeSH. NLM produces Medical Subject Headings XML, ASCII, MARC 21 and RDF formats. Updates to the data files are made according to the following schedule: MeSH XML MeSH Descriptor files updated annually MeSH Qualifier files updated annually MeSH Supplemental Concept Records (SCR) updated daily (Monday - Friday) MeSH ASCII MeSH Descriptor files updated annually MeSH Qualifier files updated annually MeSH Supplemental Concept Records (SCR) updated daily (Monday - Friday) MeSH MARC21 All files posted monthly MeSH RDF All files posted daily (Monday - Friday)