데이터셋 상세
미국
Study of Womens Health Across the Nation (SWAN) Biospecimen Repository
,The SWAN Repository is the biospecimen bank of the SWAN study. All stored specimens are from the 3,302 SWAN participants, collected across the 14 clinic visits (Baseline and 13 follow-up visits). Available biospecimen types include serum, plasma, urine and DNA which total nearly 1.8 million. Both Repository specimens and data generated through Repository studies and subsequently returned are available through the SWAN Repository. Through the Repository website, registered users can submit inquiries and applications for access to these resources.,
데이터 정보
연관 데이터
Study of Womens Health Across the Nation (SWAN) Data: Investigator Access
공공데이터포털
,The SWAN Coordinating Center provides SWAN data access to SWAN Investigators through the study website. The SWAN website provides access to longitudinal data describing the physical, biological, psychological, and social changes that occur during the menopausal transition. Data collected from 3,302 SWAN participants from Baseline through the 13th Follow-Up visit are currently available.,
The impact of incident vertebral and non-vertebral fractures on health related quality of life in postmenopausal women
공공데이터포털
Background Little empirical research has examined the multiple consequences of osteoporosis on quality of life. Methods Health related quality of life (HRQL) was examined in relationship to incident fractures in 2009 postmenopausal women 50 years and older who were seen in consultation at our tertiary care, university teaching hospital-affiliated office and who were registered in the Canadian Database of Osteoporosis and Osteopenia (CANDOO) patients. Patients were divided into three study groups according to incident fracture status: vertebral fractures, non-vertebral fractures and no fractures. Baseline assessments of anthropometric data, medical history, therapeutic drug use, and prevalent fracture status were obtained from all participants. The disease-targeted mini-Osteoporosis Quality of Life Questionnaire (mini-OQLQ) was used to measure HRQL. Results Multiple regression analyses revealed that subjects who had experienced an incident vertebral fracture had lower HRQL difference scores as compared with non-fractured participants in total score (-0.86; 95% confidence intervals (CI): -1.30, -0.43) and the symptoms (-0.76; 95% CI: -1.23, -0.30), physical functioning (-1.12; 95% CI: -1.57, -0.67), emotional functioning (-1.06; 95% CI: -1.44, -0.68), activities of daily living (-1.47; 95% CI: -1.97, -0.96), and leisure (-0.92; 95% CI: -1.37, -0.47) domains of the mini-OQLQ. Patients who experienced an incident non-vertebral fracture had lower HRQL difference scores as compared with non-fractured participants in total score (-0.47; 95% CI: -0.70, -0.25), and the symptoms (-0.25; 95% CI: -0.49, -0.01), physical functioning (-0.39; 95% CI: -0.65, -0.14), emotional functioning (-0.97; 95% CI: -1.20, -0.75) and the activities of daily living (-0.47; 95% CI: -0.73, -0.21) domains. Conclusion Quality of life decreased in patients who sustained incident vertebral and non-vertebral fractures.
목록