An Excel file including: raw data, data dictionary, and all final data sets. A PDF containing detailed equations for calculating the daily dose using the creatinine correction and UFR, figures comparing the HI between the creatinine correction and UFR, figures and tables comparing temporal trends in the MCR between the HI and potency-weighted approach, tables describing frequency of participants by cycle, temporal limit of detection by metabolite, tolerable daily intakes by phthalate, Group designation of the MCR, complete regression equations used in the regression analysis, comparison of Group counts by creatinine correction and UFR, and relative potency factors by phthalate. This dataset is associated with the following publication: Reyes, J., and P. Price. Temporal Trends in Exposures to Six Phthalates from Biomonitoring Data: Implications for Cumulative Risk. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 52(21): 12475-12483, (2018).

The file contains three files in comma separated values (.csv) format. “Reyes_EHP_Phthalates_US_metabolites.csv” contains information about the National Health and Nutrition Examination Survey (NHANES) metabolite code names along with Tolerable Daily Intake (TDI), molecular weight of the parent phthalate, molecular weight of the metabolite, and names and abbreviations of the corresponding metabolites and phthalates. “Reyes_EHP_Phthalates_US_MCR.csv” contains the following information: • Data on the surveyed individuals from the original NHANES data files that includes • Identifying information for individual; • Demographic information used in defining the creatinine levels and in investigating sub populations based on age, gender, ethnicity; • Concentration of phthalate metabolites and creatinine in urine. • Calculated values for each individual; • Daily intake of each of the six phthalate; • Hazard Quotients associated with each phthalate’s daily intake; • Values of Hazard Index and the Maximum Cumulative Ratio. “Reyes_EHP_Phthalates_US_MCR_definitions.csv” and the definitions and units of the fields in “Reyes_EHP_Phthalates_US_MCR.csv”. This dataset is associated with the following publication: Reyes, J., and P. Price. An analysis of cumulative risks based on biomonitoring data for six phthalates using the Maximum Cumulative Ratio. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 112: 77-84, (2018).

The file contains three files in comma separated values (.csv) format. “Reyes_EHP_Phthalates_US_metabolites.csv” contains information about the National Health and Nutrition Examination Survey (NHANES) metabolite code names along with Tolerable Daily Intake (TDI), molecular weight of the parent phthalate, molecular weight of the metabolite, and names and abbreviations of the corresponding metabolites and phthalates. “Reyes_EHP_Phthalates_US_MCR.csv” contains the following information: • Data on the surveyed individuals from the original NHANES data files that includes • Identifying information for individual; • Demographic information used in defining the creatinine levels and in investigating sub populations based on age, gender, ethnicity; • Concentration of phthalate metabolites and creatinine in urine. • Calculated values for each individual; • Daily intake of each of the six phthalate; • Hazard Quotients associated with each phthalate’s daily intake; • Values of Hazard Index and the Maximum Cumulative Ratio. “Reyes_EHP_Phthalates_US_MCR_definitions.csv” and the definitions and units of the fields in “Reyes_EHP_Phthalates_US_MCR.csv”. This dataset is associated with the following publication: Reyes, J., and P. Price. An analysis of cumulative risks based on biomonitoring data for six phthalates using the Maximum Cumulative Ratio. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 112: 77-84, (2018).

Publicly available dataset containing chemical exposure data. This dataset is associated with the following publication: Lin, Y., V. Morozov, A. Kadry, J. Caffrey , and W. Chou. Reconstructing population exposures to acrylamide from human monitoring data using a pharmacokinetic framework. CHEMOSPHERE. Elsevier Science Ltd, New York, NY, USA, 331: 138798, (2023).

This data supports the journal publication "Comprehensive compilation of congener profiles to support health assessment of environmental exposures to polychlorinated biphenyl mixtures" which identifies and extracts published congener profiles across 29 commercial and simulated environmental PCB mixtures, including various Aroclors, Phenoclors, Clophens, and Kanechlors, among others. This work represents the most extensive effort to date to compile and make publicly available the PCB congener profiles for mixtures with toxicological data, providing a foundation for understanding toxicological potency of PCB mixtures in the environment. This dataset is associated with the following publication: Schulz, B., L. Carlson, K. Christensen, C. Weitekamp, R. Marek, A. Martinez, K. Hornbuckle, and G. Lehmann. Comprehensive compilation of congener profiles to support health assessment of environmental exposures to polychlorinated biphenyl mixtures. ENVIRONMENTAL RESEARCH. Elsevier B.V., Amsterdam, NETHERLANDS, 263(Part 1): 120081, (2024).

The excel spreadsheet includes sample IDs and labeling information for DNA sequencing raw data. In addition, DNA concentrations for all the biofilm samples analyzed are presented. This dataset is associated with the following publication: Li, L., Y. Jeon, S. Lee, H. Ryu, J. Santodomingo, and Y. Seo. Dynamics of the Physiochemical and Community Structures of Biofilms under the Influence of Algal Organic Matter and Humic Substances. WATER RESEARCH. Elsevier Science Ltd, New York, NY, USA, 158: 136-145, (2019).

The excel spreadsheet includes sample IDs and labeling information for DNA sequencing raw data. In addition, DNA concentrations for all the biofilm samples analyzed are presented. This dataset is associated with the following publication: Li, L., Y. Jeon, S. Lee, H. Ryu, J. Santodomingo, and Y. Seo. Dynamics of the Physiochemical and Community Structures of Biofilms under the Influence of Algal Organic Matter and Humic Substances. WATER RESEARCH. Elsevier Science Ltd, New York, NY, USA, 158: 136-145, (2019).

*********** Note to Josh Harrill- I don't have a copy of the final manuscript so could you please add the description of this dataset (just delete this comment and enter or cut and paste and then it should be ready to route by clicking on 'Submit for Review' button above) **********. This dataset is associated with the following publication: Nyffeler, J., D. Haggard, C. Willis, W. Setzer, R. Judson, K. Paul-Friedman, L. Everett, and J. Harrill. Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data. SLAS Discovery. SAGE Publications, THOUSAND OAKS, CA, USA, 26(2): 292-308, (2021).

*********** Note to Josh Harrill- I don't have a copy of the final manuscript so could you please add the description of this dataset (just delete this comment and enter or cut and paste and then it should be ready to route by clicking on 'Submit for Review' button above) **********. This dataset is associated with the following publication: Nyffeler, J., D. Haggard, C. Willis, W. Setzer, R. Judson, K. Paul-Friedman, L. Everett, and J. Harrill. Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data. SLAS Discovery. SAGE Publications, THOUSAND OAKS, CA, USA, 26(2): 292-308, (2021).

This excel file contains 7 tabs, each tabs contains the data for one specific figure in the paper. Description of the data and column names is also provided in each tab. This dataset is associated with the following publication: Wang, J., D. Hallinger, A. Murr, A. Buckalew, S. Simmons, S. Laws, and T. Stoker. High-Throughput Screening and Quantitative Chemical Ranking for Sodium Iodide Symporter Inhibitors in ToxCast Phase 1 Chemical Library. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 52(9): 5417-5426, (2018).