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The relationship between FV Leiden and pulmonary embolism
Pulmonary embolism (PE) is one of the leading causes of in-patient hospital deaths. As a consequence, the identification of hemostatic variables that could identify those at risk would be important in reducing mortality. It has previously been thought that deep vein thrombosis and PE are a single disease entity and would, therefore, have the same risk factors. This view is changing, however, with the realization that the prevalence of FV Leiden, a recognized genetic risk factor for deep vein thrombosis, may be a 'milder' genetic risk factor for PE. These observations suggest that PE is not only associated with a different set of risk factors, but may be reflective of a different clot structure.
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Impact of nosocomial pneumonia on the outcome of mechanically-ventilated patients
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Background: Nosocomial pneumonia (NP) is a common complication in mechanically-ventilated patients and is considered to be one of the most common causes of morbidity and mortality. However, assessment of the associated mortality is not staightforward as it shares several risk factors with NP that confound the relationship. The aim of this study was to evaluate the impact of NP on the mortality rate in an intensive care unit. During the study period (January-December 1995) all patients under mechanical ventilation for a period > 48 h (n = 314) were prospectively evaluated, and the prognostic factors of NP, which have been identified in previous studies, were recorded. Results: Pneumonia was diagnosed in 82 patients. The overall mortality rate was 34% for patients with NP compared to 17% in those without NP. Multivariate analysis selected the following three prognostic factors as being significantly associated with a higher risk of death: the presence of multiple organ failure [odds ratio (OR) 6.71, 95% CI, P < 0.001]; the presence of adult respiratory distress syndrome (ARDS) (OR 3.03, 95% CI, P < 0.01), and simplified acute physiology score (SAPS)> 9(OR 2.89, 95% CI, P < 0.05). Conclusions: In mechanically-ventilated patients NP does not represent an independent risk factor for mortality. Markers of severity of illness were the strongest predictors for mortality.
PHIDU - Premature Mortality - Cause (PHN) 2014-2018
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This dataset, released February 2021, contains the statistics of premature mortality by various causes for people below 75 years, over the years 2014 to 2018. Causes for death include cancer (colorectal, lung, breast), diabetes, circulatory system diseases (ischaemic heart disease, cerebrovascular disease), respiratory system diseases (chronic obstructive pulmonary disease), and external causes (road traffic injuries, suicide and self-inflicted injuries) The data is by Primary Health Network (PHN) 2017 geographic boundaries based on the 2016 Australian Statistical Geography Standard (ASGS). There are 31 PHNs set up by the Australian Government. Each network is controlled by a board of medical professionals and advised by a clinical council and community advisory committee. The boundaries of the PHNs closely align with the Local Hospital Networks where possible. For more information please see the data source notes on the data. Source: Data compiled by PHIDU from deaths data based on the 2014 to 2018 Cause of Death Unit Record Files supplied by the Australian Coordinating Registry and the Victorian Department of Justice, on behalf of the Registries of Births, Deaths and Marriages and the National Coronial Information System. The population is the ABS Estimated Resident Population (ERP) for Australia, 30 June 2014 to 30 June 2018. AURIN has spatially enabled the original data. Data that was not shown/not applicable/not published/not available for the specific area ('#', '..', '^', 'np, 'n.a.', 'n.y.a.' in original PHIDU data) was removed.It has been replaced by by Blank cells. For other keys and abbreviations refer to PHIDU Keys.
NCHS - VSRR Quarterly provisional estimates for selected indicators of mortality
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Provisional estimates of death rates. Estimates are presented for each of the 15 leading causes of death plus estimates for deaths attributed to drug overdose, falls (for persons aged 65 and over), human immunodeficiency virus (HIV) disease, homicide, and firearms-related deaths.