PCA contribution of variables; stacked barplot of PFAS compounds by facility; detected concentrations and corresponding exposure–activity ratios; toxicity quotients using aquatic life benchmarks; chemical methods; microbial methods; detected inorganic compounds; detected organic compounds; PCA eigenvalues and variances; detected bacteria growth; detected bacteria growth laboratory replicates; detected organic compounds in blank samples; surrogate recovery data; toxEval exclusions; exposure–activity ratio data by compound; exposure–activity ratio data by endpoint; aquatic life benchmark data by biocategory; organic chemicals and associated endpoint data from ToxCast; USEPA aquatic life benchmarks; and effluent and urban stormwater data from Oklahoma. This dataset is not publicly accessible because: Data were generated by US Geological Survey Researchers. It can be accessed through the following means: Data were generated by US Geological Survey Researchers. Format: Data were generated by US Geological Survey Researchers. This dataset is associated with the following publication: Hubbard, L., D. Kolpin, C. Givens, B. Blackwell, P. Bradley, J. Gray, R. Lane, J. Masoner, R. McCleskey, K. Romanok, M. Sandstrom, K. Smalling, and D. Villeneuve. Food, Beverage, and Feedstock Processing Facility Wastewater: a Unique and Underappreciated Source of Contaminants to U.S. Streams. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 56(2): 1028-1040, (2022).