Dataset for ORD-033364: Identification of Novel Activators of the Metal Responsive Transcription Factor (MTF-1) Using a Gene Expression Biomarker in a Microarray Compendium

공공데이터포털

The microarray experiments examined in the study. This dataset is associated with the following publication: Jackson, A., J. Liu, B. Vallanat, C. Jones, M. Nelms, G. Patlewicz, and J. Corton. Identification of Novel Activators of the Metal Responsive Transcription Factor (MTF-1) Using a Gene Expression Biomarker in a Microarray Compendium. Metallomics. Royal Society of Chemistry, London, UK, 12(9): 1400-1415, (2020).

Dataset associated with ORD-025118: Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles

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Datasets used in ORD-025118: Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles. This dataset is associated with the following publication: Corton, C., A. Williams, and C. Yauk. Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. John Wiley & Sons, Inc, Hoboken, NJ, USA, 59(9): 772-784, (2018).

Dataset used in ORD-035008 - A Set of Six Gene Expression Biomarkers and Their Thresholds Identify Rat Liver Tumorigens in Short-Term Assays

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The links provided include the DrugMatrix-Affymetrix study, the TG-GATES study, and the TempO-Seq S1500+ study. This dataset is associated with the following publication: Lewis, R., T. Hill III, and C. Corton. A set of six Gene expression biomarkers and their thresholds identify rat liver tumorigens in short-term assays. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 443: 152547, (2020).

Datasets in Gene Expression Omnibus used in the study ORD-022075: Chemical Activation of the Constitutive Activated Receptor (CAR) Leads to Activation of Oxidant-Induced Nrf2

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Gene Expression Omnibus (GEO) accession numbers of studies used in the analysis. This dataset is associated with the following publication: Rooney, J., K. Oshida, R. Kumar, W. Baldwin, and C. Corton. Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(1): 172-189, (2019).

Datasets in Gene Expression Omnibus used in the study ORD-022075: Chemical Activation of the Constitutive Activated Receptor (CAR) Leads to Activation of Oxidant-Induced Nrf2

공공데이터포털

Gene Expression Omnibus (GEO) accession numbers of studies used in the analysis. This dataset is associated with the following publication: Rooney, J., K. Oshida, R. Kumar, W. Baldwin, and C. Corton. Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(1): 172-189, (2019).

Dataset for ORD-040059: Identification of Chemical Modulators of NF-κB Using a Gene Expression Biomarker Approach

공공데이터포털

Dataset used in ORD-040059: Identification of Chemical Modulators of NF-κB Using a Gene Expression Biomarker Approach that includes publicaly available microarray datasets. This dataset is associated with the following publication: Korunes, K., J. Liu, R. Huang, M. Xia, K. Houck, and C. Corton. A gene expression biomarker for predictive toxicology to identify chemical modulators of NF-κB. PLOS ONE. Public Library of Science, San Francisco, CA, USA, 17(2): e0261854, (2022).

Dataset for ORD-040059: Identification of Chemical Modulators of NF-κB Using a Gene Expression Biomarker Approach

공공데이터포털

Dataset used in ORD-040059: Identification of Chemical Modulators of NF-κB Using a Gene Expression Biomarker Approach that includes publicaly available microarray datasets. This dataset is associated with the following publication: Korunes, K., J. Liu, R. Huang, M. Xia, K. Houck, and C. Corton. A gene expression biomarker for predictive toxicology to identify chemical modulators of NF-κB. PLOS ONE. Public Library of Science, San Francisco, CA, USA, 17(2): e0261854, (2022).

Datasets in Gene Expression Omnibus used in the study ORD-019001: Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice.

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Accession numbers of microarray data sets used in the analysis. This dataset is associated with the following publication: Kumar, R., L. Mota, E. Litoff, J. Rooney, T. Boswell, E. Courter, C. Henderson, J. Hernandez, C. Corton, D. Moore, and W. Baldwin. Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice. PLoS ONE. Public Library of Science, San Francisco, CA, USA, 12(3): 1-24, (2017).

Dataset for ORD-033344: A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-Term Assays

공공데이터포털

Microarray experiments used in the study. This dataset is associated with the following publication: Corton, J., T. Hill, J. Sutherland, J. Stevens, and J. Rooney. A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-Term Assays. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 177(1): 11-26, (2020).

Datasets used in ORD-023401: Activation of Nrf2 in the Liver is Associated with Suppression of the Growth Hormone-Regulated STAT5b Transcription Factor

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Datasets used in ORD-023401: Activation of Nrf2 in the Liver is Associated with Suppression of the Growth Hormone-Regulated STAT5b Transcription Factor. This dataset is associated with the following publication: Rooney, J., K. Oshida, N. Vasani, B. Vallanat, N. Ryan, B. Chorley, X. Wang, D. Bell, K. Wu, L. Aleksunes, C. Klaassen, T. Kensler, and C. Corton. Activation of Nrf2 in the Liver is Associated with Suppression of the Growth Hormone-Regulated STAT5b Transcription Factor. PLoS ONE. Public Library of Science, San Francisco, CA, USA, 13(8): 1-30, (2018).