R-language data files from "Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS, Henderson WM, Richard AM, Patlewicz G, Wetmore BA, Paul Friedman K, Shafer T. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. Chem Res Toxicol. 2023 Mar 20;36(3):402-419. doi: 10.1021/acs.chemrestox.2c00344. Epub 2023 Feb 23. PMID: 36821828.". This dataset is associated with the following publication: Carstens, K., T. Freudenrich, K. Wallace, S. Choo, A. Carpenter, M. Smeltz, M. Clifton, M. Henderson, A. Richard, G. Patlewicz, B. Wetmore, K. Friedman, and T. Shafer. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 36(3): 402-419, (2023).

Study reports for "Subchronic Toxicities of Four Per- and Polyfluoroalkyl Substances (PFASs) by Oral Exposure in Sprague–Dawley Rats". This dataset is associated with the following publication: Kenyon, E., M. Devito, G. Patlewicz, L. Adams, R. Thomas, J. Ambroso, X. Yang, J. Blake, B. Upadhyay, J. Furr, and M. Hughes. Subchronic Toxicities of Four Per- and Polyfluoroalkyl Substances (PFASs) by Oral Exposure in Sprague–Dawley Rats. Toxics. MDPI, Basel, SWITZERLAND, 13(7): 524, (2025).

Data for "Smeltz MG, Clifton MS, Henderson WM, McMillan L, Wetmore BA. Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening: Analytical and testing considerations to inform a PFAS stock quality evaluation framework. Toxicol Appl Pharmacol. 2023 Jan 15;459:116355. doi: 10.1016/j.taap.2022.116355. Epub 2022 Dec 16. PMID: 36535553". This dataset is associated with the following publication: Smeltz, M., M. Clifton, W. Henderson, L. McMillan, and B. Wetmore. Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening: Analytical and testing considerations to inform a PFAS stock quality evaluation framework. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 459: 116355, (2023).

Data for "Smeltz MG, Clifton MS, Henderson WM, McMillan L, Wetmore BA. Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening: Analytical and testing considerations to inform a PFAS stock quality evaluation framework. Toxicol Appl Pharmacol. 2023 Jan 15;459:116355. doi: 10.1016/j.taap.2022.116355. Epub 2022 Dec 16. PMID: 36535553". This dataset is associated with the following publication: Smeltz, M., M. Clifton, W. Henderson, L. McMillan, and B. Wetmore. Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening: Analytical and testing considerations to inform a PFAS stock quality evaluation framework. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 459: 116355, (2023).

Dataset includes summary statistics (mean, standard error, sample size) for all endpoints measured and reported from the the experiments described in the published manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, J. Bangma, J. Ford, D. Jenkins-Hill, E. Medlock Kakaley, and L. Gray. Maternal and neonatal effects of maternal oral exposure to perfluoro-2-methoxyacetic acid (PFMOAA) during pregnancy and early lactation in the Sprague-Dawley rat. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 58(2): 1064-1075, (2024).

Data processing was conducted using the Anaconda distribution of Python 3.9 and associated libraries. Jupyter notebooks are available at https://github.com/patlewig/nts_pfas. Datasets supporting the manuscript are accessible at https://doi.org/10.23645/epacomptox.26524327. This dataset is associated with the following publication: Patlewicz, G., R. Judson, A. Williams, T. Butler, S. Barone, K. Carstens, J. Cowden, J. Dawson, S. Degitz, K. Fay, A. Lowit, S. Padilla, K. Friedman, M. Phillips, D. Turk, J. Wambaugh, B. Wetmore, and R. Thomas. Development of chemical categories for per- and polyfluoroalkyl substances (PFAS) and the proof-of-concept approach to the identification of potential candidates for tiered toxicological testing and human health assessment. Computational Toxicology. Elsevier B.V., Amsterdam, NETHERLANDS, 31: 100327, (2024).

Contains values from pbpk models for each study on n-butanol effects. This dataset is associated with the following publication: Segal, D., A. Bale, L. Phillips, A. Sasso, P. Schlosser, C. Starkey, and S. Makris. Issues in Assessing the Health Risks of n-Butanol. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 40(1): 72-86, (2020).

Contains values from pbpk models for each study on n-butanol effects. This dataset is associated with the following publication: Segal, D., A. Bale, L. Phillips, A. Sasso, P. Schlosser, C. Starkey, and S. Makris. Issues in Assessing the Health Risks of n-Butanol. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 40(1): 72-86, (2020).

Supplementary material for "Kreutz, A.; Clifton, M.S.; Henderson, W.M.; Smeltz, M.G.; Phillips, M.; Wambaugh, J.F.; Wetmore, B.A. Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry. Toxics 2023, 11, 463. https://doi.org/10.3390/toxics11050463". This dataset is associated with the following publication: Kreutz, A., M. Clifton, W. Henderson, M. Smeltz, M. Phillips, J. Wambaugh, and B. Wetmore. Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry. Toxics. MDPI, Basel, SWITZERLAND, 11(5): 463, (2023).

Supplementary material for "Kreutz, A.; Clifton, M.S.; Henderson, W.M.; Smeltz, M.G.; Phillips, M.; Wambaugh, J.F.; Wetmore, B.A. Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry. Toxics 2023, 11, 463. https://doi.org/10.3390/toxics11050463". This dataset is associated with the following publication: Kreutz, A., M. Clifton, W. Henderson, M. Smeltz, M. Phillips, J. Wambaugh, and B. Wetmore. Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry. Toxics. MDPI, Basel, SWITZERLAND, 11(5): 463, (2023).