Dataset includes summary statistics (mean, standard error, sample size) for all endpoints measured and reported in the experiments described in the published manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, A. Farraj, J. Smoot, R. Grindstaff, D. Jenkins-Hill, J. McCord, E. Medlock Kakaley, A. Dixon, E. Hines, and L. Gray. Dose additive maternal and offspring effects of oral maternal exposure to a mixture of three PFAS (HFPO-DA, NBP2, PFOS) during pregnancy in the Sprague-Dawley rat. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 892: 164609, (2023).

Data for individual animals used to create the information demonstrated in Table 1 of the manuscript, including PFESA BP2 serum and liver concentrations and serum clinical chemistry values. This dataset is associated with the following publication: Jenkins-Hill, D., M. Strynar, A. Lindstrom, A. Farthing, H. Huang, J. Schmid, J. Lang, and N. Chernoff. Toxicity of Balb-c mice exposed to recently identified 1,1,2,2-tetrafluoro-2-[1,1,1,2,3,3-hexafluoro-3-(1,1,2,2-tetrafluoroethoxy)propan-2-yl]oxyethane-1-sulfonic acid (PFESA-BP2). TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441(152529): 1, (2020).

Dataset contains summary data (mean, standard error, sample size (n)) for all measured endpoints reported and depicted in the corresponding manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, M. Strynar, J. McCord, B. McIntyre, G. Travlos, M. Cardon, E. MedlockKakaley, P. Hartig, V. Wilson, and E. Gray. Adverse maternal, fetal, and postnatal effects of Hexafluoropropylene oxide dimer acid (GenX) from oral gestational exposure in Sprague Dawley rats. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 1-13, (2019).

Dataset contains summary data (mean, standard error, sample size (n)) for all measured endpoints reported and depicted in the corresponding manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, M. Strynar, J. McCord, B. McIntyre, G. Travlos, M. Cardon, E. MedlockKakaley, P. Hartig, V. Wilson, and E. Gray. Adverse maternal, fetal, and postnatal effects of Hexafluoropropylene oxide dimer acid (GenX) from oral gestational exposure in Sprague Dawley rats. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 1-13, (2019).

R-language data files from "Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS, Henderson WM, Richard AM, Patlewicz G, Wetmore BA, Paul Friedman K, Shafer T. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. Chem Res Toxicol. 2023 Mar 20;36(3):402-419. doi: 10.1021/acs.chemrestox.2c00344. Epub 2023 Feb 23. PMID: 36821828.". This dataset is associated with the following publication: Carstens, K., T. Freudenrich, K. Wallace, S. Choo, A. Carpenter, M. Smeltz, M. Clifton, M. Henderson, A. Richard, G. Patlewicz, B. Wetmore, K. Friedman, and T. Shafer. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 36(3): 402-419, (2023).

R-language data files from "Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS, Henderson WM, Richard AM, Patlewicz G, Wetmore BA, Paul Friedman K, Shafer T. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. Chem Res Toxicol. 2023 Mar 20;36(3):402-419. doi: 10.1021/acs.chemrestox.2c00344. Epub 2023 Feb 23. PMID: 36821828.". This dataset is associated with the following publication: Carstens, K., T. Freudenrich, K. Wallace, S. Choo, A. Carpenter, M. Smeltz, M. Clifton, M. Henderson, A. Richard, G. Patlewicz, B. Wetmore, K. Friedman, and T. Shafer. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 36(3): 402-419, (2023).

File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for nuclear receptors at 24 h post-treatment. This dataset is associated with the following publication: Lau, C., J. Rumpler, K. Das, C. Wood, J. Schmid, M. Strynar, and J. Wambaugh. Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441: 152522, (2020).

data set has a description of the information in the excell file and all the data used in the study. This dataset is associated with the following publication: Gray, E., J. Conley, C. Lambright, and J. Furr. In utero exposure to a mixture of the perfluoroalkylisopropyl pesticide pyrifluquinazon with dibutyl phthalate cumulatively disrupts male rat reproductive development via different mechanisms of action. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(2): 234-247, (2022).

data set has a description of the information in the excell file and all the data used in the study. This dataset is associated with the following publication: Gray, E., J. Conley, C. Lambright, and J. Furr. In utero exposure to a mixture of the perfluoroalkylisopropyl pesticide pyrifluquinazon with dibutyl phthalate cumulatively disrupts male rat reproductive development via different mechanisms of action. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(2): 234-247, (2022).

Maternal and fetal liver gene expression and pathway changes following exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA) during gestation. This dataset is associated with the following publication: Blake, B., C. Miller, H. Nguyen, V. Chappell, T. Phan, D. Phadke, M. Balik-Meisner, D. Mav, R. Shah, and S. Fenton. Transcriptional pathways linked to fetal and maternal hepatic dysfunction caused by gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) in CD-1 mice. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. Elsevier Science Ltd, New York, NY, USA, 248: 114314, (2022).