These data are a result of an experiment to examine the effect of imidacloprid on chicken immunity and behavior. There are therefore several sets of physiological data. Citation information for this dataset can be found in the EDG's Metadata Reference Information section and Data.gov's References section.

The dataset includes information on birds used in the study and the samples collected as well as imidacloprid and imidacloprid metabolite data. The first author should be contacted prior to using these data at charlotte.roy@state.mn.us. Citation information for this dataset can be found in the EDG's Metadata Reference Information section and Data.gov's References section.

,To enhance the efficacy of the current Newcastle disease vaccine, we have tested two potential adjuvants (Imiquimod and ODN-1826) in chickens. Birds were treated with PBS, Imiquimod or ODN-1826 (50 µg/bird) or vaccinated intranasally with live LaSota strain with or without Imiquimod or ODN-1826 (50 µg/bird). Two weeks after vaccination, birds were challenged with virulent New-castle disease virus (chicken/CA/212676/2002). The experimental setting was a laboratory with animal care as approved by the institutional animal care and use committee as appropriate for the species and age of bird. Data are the serum antibody titers to the vaccine or challenge virus as determined by hemagglutination inhibition assay. Virus shedding titers by the oral and cloacal route for individual birds exposed to virulent Newcastle disease virus were determined by quantitative real-time RT-PCR. Expression of antiviral genes from tissues collected at 1 and 3 days after treating 2 week old SPF chickens with adjuvant and/or vaccines were determined by quantitative PCR.,Resources in this dataset:,

This work is part of a study of the immunological effects of exposure to alternative flame retardants in avian species. For the pathology portion of the study, spleens and bursas from American kestrels (Falco sparverius) exposed by egg injection to varying doses of short-chain chlorinated paraffins (SCCPs) and the flame retardant TBBPA-BDBPE were examined microscopically for architectural and cellular abnormalities. At euthanasia, spleen and bursa of Fabricius were collected and fixed in 10% neutral buffered formalin for histopathological assessment. Slides were processed and stained with hematoxalin and eosin as per standard procedure (Luna 1968). Quantitative and qualitative B and T cell parameters were assessed by light microscopy. Specifically, variables assessed included the following: spleen: total area; number, thickness and area of peri-arteriolar lymphoid sheaths; number and diameter of lymphoid follicles; bursa: follicular and medullary area; cellular density; apoptosis; heterophil infiltration; presence of follicular cysts. Evaluation of the architecture and cellular population of immune organs will shed light on potential functional immunological effects of exposure that may lead to increased susceptibility to infectious disease or affect normal growth and development of the chick. (Luna LG. 1968. Manual of histologic staining methods of the armed forces institute of pathology, 3rd edn. McGraw-Hill, New York, NY.)

This work is part of a study of the immunological effects of exposure to alternative flame retardants in avian species. For the pathology portion of the study, spleens and bursas from American kestrels (Falco sparverius) exposed by egg injection to varying doses of short-chain chlorinated paraffins (SCCPs) and the flame retardant TBBPA-BDBPE were examined microscopically for architectural and cellular abnormalities. At euthanasia, spleen and bursa of Fabricius were collected and fixed in 10% neutral buffered formalin for histopathological assessment. Slides were processed and stained with hematoxalin and eosin as per standard procedure (Luna 1968). Quantitative and qualitative B and T cell parameters were assessed by light microscopy. Specifically, variables assessed included the following: spleen: total area; number, thickness and area of peri-arteriolar lymphoid sheaths; number and diameter of lymphoid follicles; bursa: follicular and medullary area; cellular density; apoptosis; heterophil infiltration; presence of follicular cysts. Evaluation of the architecture and cellular population of immune organs will shed light on potential functional immunological effects of exposure that may lead to increased susceptibility to infectious disease or affect normal growth and development of the chick. (Luna LG. 1968. Manual of histologic staining methods of the armed forces institute of pathology, 3rd edn. McGraw-Hill, New York, NY.)

This data set is composed of data collected from an experimental study inoculating mallard ducks (Anas platyrhynchos) with Saxitoxin and associated control ducks. Data includes the specific of inoculation, observational behavioral data, daily weights, dosing, results of inoculation, testing of samples collected throughout the study, and necropsy results.

This data set is composed of data collected from an experimental study inoculating mallard ducks (Anas platyrhynchos) with Saxitoxin and associated control ducks. Data includes the specific of inoculation, observational behavioral data, daily weights, dosing, results of inoculation, testing of samples collected throughout the study, and necropsy results.

- Observations of test subjects, - Body weight, organ/tissue weights - Biomarker data (oxidative DNA damage, thyroid hormones, corticosterone, gene expression) in various tissues - Residues as percent of administered dose - Tissues to plasma rations - Metabolites and ratios - Elimination half-lives

- Observations of test subjects, - Body weight, organ/tissue weights - Biomarker data (oxidative DNA damage, thyroid hormones, corticosterone, gene expression) in various tissues - Residues as percent of administered dose - Tissues to plasma rations - Metabolites and ratios - Elimination half-lives

- Observations of test subjects, - Body weight Reproductive Data for All Nests Monitored - Estimates of test diet consumption - Hematocrit - Clotting time parameters (prothrombin time, Russell’s viper venom time, fibrinogen concentration)