Datasets used in ORD-025118: Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles. This dataset is associated with the following publication: Corton, C., A. Williams, and C. Yauk. Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. John Wiley & Sons, Inc, Hoboken, NJ, USA, 59(9): 772-784, (2018).

Datasets used in ORD-025118: Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles. This dataset is associated with the following publication: Corton, C., A. Williams, and C. Yauk. Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. John Wiley & Sons, Inc, Hoboken, NJ, USA, 59(9): 772-784, (2018).

Accession numbers of microarray data sets used in the analysis. This dataset is associated with the following publication: Kumar, R., L. Mota, E. Litoff, J. Rooney, T. Boswell, E. Courter, C. Henderson, J. Hernandez, C. Corton, D. Moore, and W. Baldwin. Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice. PLoS ONE. Public Library of Science, San Francisco, CA, USA, 12(3): 1-24, (2017).

We used systematic evidence map methods to summarize the available epidemiological and animal bioassay evidence for an expanded set of ~345 PFAS that were prioritized in 2019 by the EPA’s Center for Computational Toxicology and Exposure (CCTE) for in vitro toxicity and toxicokinetic screening. This work builds upon our previously published evidence map for ~150 PFAS chemicals (Carlson et al. 2022, https://doi.org/10.1289/EHP10343). This dataset is associated with the following publication: Shirke, A., E. Radke-Farabaugh, C. Lin, R. Blain, N. Vetter, c. lemeris, p. hartman, H. Hubbard, M. Angrish, X. Arzuaga Andino, J. Congleton, J. Davis, L. Dishaw, R. Jones, R. Judson, J. Kaiser, A. Kraft, L. Lizarraga, P. Noyes, G. Patlewicz, M. Taylor, A. Williams, K. Chialton, and L. Carlson. Expanded Systematic Evidence Map for Hundreds of Per- and Polyfluoroalkyl Substances (PFAS) and Comprehensive PFAS Human Health Dashboard. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 132(2): CID: 026001, (2024).

Gene Expression Omnibus and ArrayExpress archived study numbers of microarray data used in the study. This dataset is associated with the following publication: Rooney, J., B. Chorley, S. Hiemstra, S. Wink, X. Wang, D. Bell, B. van de Water, and J. Corton. Mining a human transcriptome database for chemical modulators of Nrf2 (PLOS ONE). PLoS ONE. Public Library of Science, San Francisco, CA, USA, 15(9): e0239367, (2020).

The microarray experiments examined in the study. This dataset is associated with the following publication: Jackson, A., J. Liu, B. Vallanat, C. Jones, M. Nelms, G. Patlewicz, and J. Corton. Identification of Novel Activators of the Metal Responsive Transcription Factor (MTF-1) Using a Gene Expression Biomarker in a Microarray Compendium. Metallomics. Royal Society of Chemistry, London, UK, 12(9): 1400-1415, (2020).

Microarray experiments used in the study. This dataset is associated with the following publication: Corton, J., T. Hill, J. Sutherland, J. Stevens, and J. Rooney. A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-Term Assays. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 177(1): 11-26, (2020).

The links provided include the DrugMatrix-Affymetrix study, the TG-GATES study, and the TempO-Seq S1500+ study. This dataset is associated with the following publication: Lewis, R., T. Hill III, and C. Corton. A set of six Gene expression biomarkers and their thresholds identify rat liver tumorigens in short-term assays. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 443: 152547, (2020).

Dataset of medium throughput (96 well plate) in vitro nuclear receptor activation assays for peroxisome proliferator activated receptor alpha (PPARa), PPAR gamma (PPARg), and estrogen receptor (ER) across a panel of per- and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals. This dataset is associated with the following publication: Evans, N., J. Conley, M. Cardon, P. Hartig, E. Medlock Kakaley, and L. Gray. In vitro activity of a panel of per- and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals in peroxisome proliferator-activated receptor (PPAR) alpha, PPAR gamma, and estrogen receptor. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 449(116136): 1, (2022).

Dataset of medium throughput (96 well plate) in vitro nuclear receptor activation assays for peroxisome proliferator activated receptor alpha (PPARa), PPAR gamma (PPARg), and estrogen receptor (ER) across a panel of per- and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals. This dataset is associated with the following publication: Evans, N., J. Conley, M. Cardon, P. Hartig, E. Medlock Kakaley, and L. Gray. In vitro activity of a panel of per- and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals in peroxisome proliferator-activated receptor (PPAR) alpha, PPAR gamma, and estrogen receptor. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 449(116136): 1, (2022).