Data for individual animals used to create the information demonstrated in Table 1 of the manuscript, including PFESA BP2 serum and liver concentrations and serum clinical chemistry values. This dataset is associated with the following publication: Jenkins-Hill, D., M. Strynar, A. Lindstrom, A. Farthing, H. Huang, J. Schmid, J. Lang, and N. Chernoff. Toxicity of Balb-c mice exposed to recently identified 1,1,2,2-tetrafluoro-2-[1,1,1,2,3,3-hexafluoro-3-(1,1,2,2-tetrafluoroethoxy)propan-2-yl]oxyethane-1-sulfonic acid (PFESA-BP2). TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441(152529): 1, (2020).

Zipped UCMR3 data. This dataset is associated with the following publication: HU, X., D. Andrews, T. Bruton, A. Lindstrom, L. Schaider, P. Grandjean, R. Lohmann, C. Carignan, A. Blum, S. Balan, E. Sunderland, and C. Higgins. Detection of Poly- and Perfluoroalkyl Substances (PFASs) in U.S. Dinking Water: Linked to Industrial Sites, Military fire Training Areas and Wastewater Treatment Plants. Environmental Science & Technology Letters. American Chemical Society, Washington, DC, USA, 3(0): 344-350, (2017).

Zipped UCMR3 data. This dataset is associated with the following publication: HU, X., D. Andrews, T. Bruton, A. Lindstrom, L. Schaider, P. Grandjean, R. Lohmann, C. Carignan, A. Blum, S. Balan, E. Sunderland, and C. Higgins. Detection of Poly- and Perfluoroalkyl Substances (PFASs) in U.S. Dinking Water: Linked to Industrial Sites, Military fire Training Areas and Wastewater Treatment Plants. Environmental Science & Technology Letters. American Chemical Society, Washington, DC, USA, 3(0): 344-350, (2017).

These data were part of a critical review that looks at the occurrence of PFOS in ambient surface waters across the U.S. All data from this paper were obtained from publicly available literature, including peer-review journal articles, theses, and government and industry reports through 2020. These data include measured PFOS concentrations across the U.S., sample site location (i.e., state, waterbody, and GPS coordinates), and dates of sample collection and analysis, and analytical methods used. Citation information for this dataset can be found in the EDG's Metadata Reference Information section and Data.gov's References section.

Data were generated at the University of Florida. This dataset is not publicly accessible because: Data are not owned by EPA/ORD. It can be accessed through the following means: contact the study lead Dr. Timothy Townsend (ttown@ufl.edu). Format: Data were generated at the University of Florida. This dataset is associated with the following publication: Thompson, J., N. Robey, T. Tolaymat, J. Bowden, H.M. Solo-Gabriele, and T. Townsend. Underestimation of Per- and Polyfluoroalkyl Substances in Biosolids: Precursor Transformation During Conventional Treatment. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 57(9): 3825-3832, (2023).

PFAS concentrations in blood serum. This dataset is not publicly accessible because: Data is the property of the research leads (NC State University). It can be accessed through the following means: Contact Jane Hoppin of NC State University (jahoppin@ncsu.edu). Format: Data is quantitative measurements of blood serum levels for PFAS levels in human serum formated as MS Raw files and instrument vendor quantification files. This dataset is associated with the following publication: Kotlarz, N., J. McCord, D. Collier, C.S. Lea, M. Strynar, A. Lindstrom, A.A. Wilkie, J.Y. Islam, K. Matney, P. Tarte, M. Polera, K. Burdette, J. DeWitt, K. May, R.C. Smart, D.R.U. Knappe, and J.A. Hoppin. Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 128(7): 77005, (2020).

Raw data (peak area and height, retention time) for each mass transition for each sample. This dataset is associated with the following publication: Miller, K., and M. Strynar. Improved Tandem Mass Spectrometry Detection and Resolution of Low Molecular Weight Perfluoroalkyl Ether Carboxylic Acid Isomers. Environmental Science & Technology Letters. American Chemical Society, Washington, DC, USA, 9(9): 747-751, (2022).

Raw data (peak area and height, retention time) for each mass transition for each sample. This dataset is associated with the following publication: Miller, K., and M. Strynar. Improved Tandem Mass Spectrometry Detection and Resolution of Low Molecular Weight Perfluoroalkyl Ether Carboxylic Acid Isomers. Environmental Science & Technology Letters. American Chemical Society, Washington, DC, USA, 9(9): 747-751, (2022).

Supporting information for manuscript, including chromatograms, peak areas, and standard recovery data to support PFAS manuscript. This dataset is associated with the following publication: Sanan, T., and M. Magnuson. Analysis of per- and polyfluorinated alkyl substances (PFAS) of sub-sampled water matrices with online solid phase extraction/isotope dilution tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY A. Elsevier Science Ltd, New York, NY, USA, 1626: 461324, (2020).

File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for nuclear receptors at 24 h post-treatment. This dataset is associated with the following publication: Lau, C., J. Rumpler, K. Das, C. Wood, J. Schmid, M. Strynar, and J. Wambaugh. Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441: 152522, (2020).