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PFAS levels in blood serum in Wilmington, NC
PFAS concentrations in blood serum. This dataset is not publicly accessible because: Data is the property of the research leads (NC State University). It can be accessed through the following means: Contact Jane Hoppin of NC State University (jahoppin@ncsu.edu). Format: Data is quantitative measurements of blood serum levels for PFAS levels in human serum formated as MS Raw files and instrument vendor quantification files. This dataset is associated with the following publication: Kotlarz, N., J. McCord, D. Collier, C.S. Lea, M. Strynar, A. Lindstrom, A.A. Wilkie, J.Y. Islam, K. Matney, P. Tarte, M. Polera, K. Burdette, J. DeWitt, K. May, R.C. Smart, D.R.U. Knappe, and J.A. Hoppin. Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 128(7): 77005, (2020).
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PFAS levels in blood serum in Wilmington, NC
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PFAS concentrations in blood serum. This dataset is not publicly accessible because: Data is the property of the research leads (NC State University). It can be accessed through the following means: Contact Jane Hoppin of NC State University (jahoppin@ncsu.edu). Format: Data is quantitative measurements of blood serum levels for PFAS levels in human serum formated as MS Raw files and instrument vendor quantification files. This dataset is associated with the following publication: Kotlarz, N., J. McCord, D. Collier, C.S. Lea, M. Strynar, A. Lindstrom, A.A. Wilkie, J.Y. Islam, K. Matney, P. Tarte, M. Polera, K. Burdette, J. DeWitt, K. May, R.C. Smart, D.R.U. Knappe, and J.A. Hoppin. Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 128(7): 77005, (2020).
Biosolids PFAS data
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Data were generated at the University of Florida. This dataset is not publicly accessible because: Data are not owned by EPA/ORD. It can be accessed through the following means: contact the study lead Dr. Timothy Townsend (ttown@ufl.edu). Format: Data were generated at the University of Florida. This dataset is associated with the following publication: Thompson, J., N. Robey, T. Tolaymat, J. Bowden, H.M. Solo-Gabriele, and T. Townsend. Underestimation of Per- and Polyfluoroalkyl Substances in Biosolids: Precursor Transformation During Conventional Treatment. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 57(9): 3825-3832, (2023).
Biological Measurements for Dosed Model Organism
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Serum PFAS concentrations, pup weights, liver histopathology measurements, lipid panels, fasting insulin measurements. This dataset is not publicly accessible because: Data is the property of NIH. It can be accessed through the following means: Contact Suzanne Fenton for data (suzane.fenton@nih.gov). Format: Data stored in excel database format. This dataset is associated with the following publication: Cope, H.A., B.E. Blake, C. Love, J. McCord, S.A. Elmore, J.B. Harvey, V.A. Chappell, and S.E. Fenton. Latent, sex-specific metabolic health effects in CD-1 mouse offspring exposed to PFOA or HFPO-DA (GenX) during gestation. Emerging Contaminants. Elsevier B.V., Amsterdam, NETHERLANDS, 7: 219-235, (2021).
Cardinal Serum Concentrations and Metadata 11/20/2017
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Measured Concentrations of PFASs in all samples is provided. Calculations of the method accuracy using SRM 1957 and method precision using replicate analysis is provided. Metadata for all cardinals is provided. This dataset is associated with the following publication: Russell, M., S. Newton, K. McClure, R. Levine, L. Phelps, A. Lindstrom, and M. Strynar. Per- and polyfluoroalkyl substances in two different populations of northern cardinals. CHEMOSPHERE. Elsevier Science Ltd, New York, NY, USA, 222: 295-304, (2019).
NCS PFAS dietary data
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Food frequency questionnaire data compared to PFAS measurements in serum of pregnant women enrolled in the National Children's Study. This dataset is not publicly accessible because: Data are not available from the authors as they were obtained through Data Use Agreements. It can be accessed through the following means: Create a Data Use Agreement with NCS Vanguard Data and Sample Archive and Access System and the NICHD Data and Specimen Hub (DASH). Format: This manuscript was prepared using National Children’s Study Research Materials obtained from the NCS Vanguard Data and Sample Archive and Access System and the NICHD Data and Specimen Hub (DASH). This dataset is associated with the following publication: Deluca, N., K. Thomas, T. Luben, and L. Melnyk. Associations between self-reported consumption of foods and serum PFAS concentrations in a sample of pregnant women in the United States. ENVIRONMENTAL RESEARCH. Elsevier B.V., Amsterdam, NETHERLANDS, 276: 121461, (2025).
PFESABP2v01
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Data for individual animals used to create the information demonstrated in Table 1 of the manuscript, including PFESA BP2 serum and liver concentrations and serum clinical chemistry values. This dataset is associated with the following publication: Jenkins-Hill, D., M. Strynar, A. Lindstrom, A. Farthing, H. Huang, J. Schmid, J. Lang, and N. Chernoff. Toxicity of Balb-c mice exposed to recently identified 1,1,2,2-tetrafluoro-2-[1,1,1,2,3,3-hexafluoro-3-(1,1,2,2-tetrafluoroethoxy)propan-2-yl]oxyethane-1-sulfonic acid (PFESA-BP2). TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441(152529): 1, (2020).
Estimation of species- and sex-specific PFAS pharmacokinetics in mice, rats, and non-human primates using a Bayesian hierarchical methodology dataset
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This dataset is a collection of .csv's for extracted data from the literature, processing code, and final analysis for manuscript. This dataset is not publicly accessible because: This data is subject to change following peer review. It can be accessed through the following means: This data will be publicly accessible on github once the manuscript is accepted for publication. Format: This is the extracted data, code, and documentation for this manuscript. This dataset is associated with the following publication: Zurlinden, T., M. Dzierlenga, D. Kapraun, C. Ring, A. Bernstein, P. Schlosser, and V. Morozov. Estimation of species- and sex-specific PFAS pharmacokinetics in mice, rats, and non-human primates using a Bayesian hierarchical methodology. TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier B.V., Amsterdam, NETHERLANDS, 499: 117336, (2025).
Ex-R Study Urine Data
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Emory University (analyzed the urine samples for pyrethroid metabolites). This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: Contact Researcher. Format: Pyrethroid metabolite concentration data for 50 adults over six-weeks. This dataset is associated with the following publication: Morgan , M., J. Sobus , D.B. Barr, C. Croghan , F. Chen , R. Walker, L. Alston, E. Andersen, and M. Clifton. Temporal variability of pyrethroid metabolite levels in bedtime, morning, and 24-hr urine samples for 50 adults in North Carolina. ENVIRONMENT INTERNATIONAL. Elsevier Science Ltd, New York, NY, USA, 144: 81-91, (2015).
New Jersey NJDEP/EPA-ORD soil PFAS study
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The toxicity and environmental persistence of anthropogenic per- and poly-fluoroalkyl substances (PFAS) are of concern globally. To address legacy PFAS concerns in the US, industry developed numerous replacement PFAS that commonly are treated as confidential information. To investigate the distribution of PFAS in New Jersey (NJ), soils collected from across the state were subjected to nontargeted mass-spectral analyses. Ten chloro-perfluoro-polyether-carboxylates were tentatively identified, with ≥3 congeners in all samples. Nine congeners are ≥(CF2)7. Distinct chemical formulas and structures, as well as geographic distribution, suggest airborne transport from an industrial source. Lighter congeners dispersed more widely than heavier, with the most widely dispersed detected in an in-stock New Hampshire sample. Additional data were used to develop a legacy-PFAS fingerprint for historical PFAS sources in NJ. This dataset is associated with the following publication: Washington, J., C. Rosal, J. McCord, M. Strynar, A. Lindstrom, E. Bergman, S. Goodrow, H. Tadesse, D. Pilant, B. Washington, M.J. Davis, B. Stuart, and T. Jenkins. Nontargeted mass-spectral detection of chloroperfluoropolyether carboxylates in New Jersey soils. SCIENCE. American Association for the Advancement of Science (AAAS), Washington, DC, USA, 368(6495): 1103-1107, (2020).
Fluorine measurements for target PFAS and PFAS mixtures
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Fluorine measurements for target PFAS and PFAS mixtures, fluorine mass balance calculations, non-targeted compound abundances. This dataset is not publicly accessible because: All data not included in the manuscript supplemental information is property of Harvard University. It can be accessed through the following means: Contact: Elsie Sunderland (ems@seas.harvard.edu). Format: Manuscript supplemental information contains tables of outputs of various assays in terms of concentrations. This dataset is associated with the following publication: Ruyle, B.J., C.P. Thackray, J. McCord, M. Strynar, K.A. Mauge-Lewis, S.E. Fenton, and E.M. Sunderland. Reconstructing the Composition of Per- and Polyfluoroalkyl Substances in Contemporary Aqueous Film-Forming Foams. Environmental Science & Technology Letters. American Chemical Society, Washington, DC, USA, 8(1): 59-65, (2021).