This dataset is a collection of .csv's for extracted data from the literature, processing code, and final analysis for manuscript. This dataset is not publicly accessible because: This data is subject to change following peer review. It can be accessed through the following means: This data will be publicly accessible on github once the manuscript is accepted for publication. Format: This is the extracted data, code, and documentation for this manuscript. This dataset is associated with the following publication: Zurlinden, T., M. Dzierlenga, D. Kapraun, C. Ring, A. Bernstein, P. Schlosser, and V. Morozov. Estimation of species- and sex-specific PFAS pharmacokinetics in mice, rats, and non-human primates using a Bayesian hierarchical methodology. TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier B.V., Amsterdam, NETHERLANDS, 499: 117336, (2025).

Data set 1 consists of the experimental data for the Wild Type and PPAR KO animal study and includes data used to prepare Figures 1-4 and Table 1 of the Das et al, 2016 paper. This dataset is associated with the following publication: Das, K., C. Wood, M. Lin, A.A. Starkov, C. Lau, K.B. Wallace, C. Corton, and B. Abbott. Perfluoroalky acids-induced liver steatosis: Effects on genes controlling lipid homeostasis. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 378: 32-52, (2017).

Data set 1 consists of the experimental data for the Wild Type and PPAR KO animal study and includes data used to prepare Figures 1-4 and Table 1 of the Das et al, 2016 paper. This dataset is associated with the following publication: Das, K., C. Wood, M. Lin, A.A. Starkov, C. Lau, K.B. Wallace, C. Corton, and B. Abbott. Perfluoroalky acids-induced liver steatosis: Effects on genes controlling lipid homeostasis. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 378: 32-52, (2017).

Data were generated at the University of Florida. This dataset is not publicly accessible because: Data are not owned by EPA/ORD. It can be accessed through the following means: contact the study lead Dr. Timothy Townsend (ttown@ufl.edu). Format: Data were generated at the University of Florida. This dataset is associated with the following publication: Thompson, J., N. Robey, T. Tolaymat, J. Bowden, H.M. Solo-Gabriele, and T. Townsend. Underestimation of Per- and Polyfluoroalkyl Substances in Biosolids: Precursor Transformation During Conventional Treatment. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 57(9): 3825-3832, (2023).

File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for nuclear receptors at 24 h post-treatment. This dataset is associated with the following publication: Lau, C., J. Rumpler, K. Das, C. Wood, J. Schmid, M. Strynar, and J. Wambaugh. Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441: 152522, (2020).

File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for nuclear receptors at 24 h post-treatment. This dataset is associated with the following publication: Lau, C., J. Rumpler, K. Das, C. Wood, J. Schmid, M. Strynar, and J. Wambaugh. Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441: 152522, (2020).

Dataset for Identification of Biomarkers of Exposure to FTOHs and PAPs in Humans Using a Targeted and Non-targeted Analysis Approach. This dataset is associated with the following publication: Dagnino, A., M. Strynar, R. McMahen, C. Lau, C. Ball, S. Garantziosis, T. Webster, M. McClean, and A. Lindstrom. Identification of Biomarkers of Exposure to FTOHs and PAPs in Humans Using a Targeted and Non-targeted Analysis Approach. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 50(0): 10216-10225, (2016).

Dataset includes summary statistics (mean, standard error, sample size) for all endpoints measured and reported from the the experiments described in the published manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, J. Bangma, J. Ford, D. Jenkins-Hill, E. Medlock Kakaley, and L. Gray. Maternal and neonatal effects of maternal oral exposure to perfluoro-2-methoxyacetic acid (PFMOAA) during pregnancy and early lactation in the Sprague-Dawley rat. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 58(2): 1064-1075, (2024).

PFAS concentrations in blood serum. This dataset is not publicly accessible because: Data is the property of the research leads (NC State University). It can be accessed through the following means: Contact Jane Hoppin of NC State University (jahoppin@ncsu.edu). Format: Data is quantitative measurements of blood serum levels for PFAS levels in human serum formated as MS Raw files and instrument vendor quantification files. This dataset is associated with the following publication: Kotlarz, N., J. McCord, D. Collier, C.S. Lea, M. Strynar, A. Lindstrom, A.A. Wilkie, J.Y. Islam, K. Matney, P. Tarte, M. Polera, K. Burdette, J. DeWitt, K. May, R.C. Smart, D.R.U. Knappe, and J.A. Hoppin. Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 128(7): 77005, (2020).

PFAS concentrations in blood serum. This dataset is not publicly accessible because: Data is the property of the research leads (NC State University). It can be accessed through the following means: Contact Jane Hoppin of NC State University (jahoppin@ncsu.edu). Format: Data is quantitative measurements of blood serum levels for PFAS levels in human serum formated as MS Raw files and instrument vendor quantification files. This dataset is associated with the following publication: Kotlarz, N., J. McCord, D. Collier, C.S. Lea, M. Strynar, A. Lindstrom, A.A. Wilkie, J.Y. Islam, K. Matney, P. Tarte, M. Polera, K. Burdette, J. DeWitt, K. May, R.C. Smart, D.R.U. Knappe, and J.A. Hoppin. Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 128(7): 77005, (2020).