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Conley 2021 NBP2 Dev tox Dataset 2022-1-10.xlsx
Dataset contains summary data (mean +/- error) for all endpoints measured in published studies. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, D. Jenkins-Hill, J. McCord, M. Strynar, L. Wehmas, S. Hester, D. Macmillan, and L. Gray. Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS). ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 160(107056): 1, (2022).
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Conley 2021 NBP2 Dev tox Dataset 2022-1-10.xlsx
공공데이터포털
Dataset contains summary data (mean +/- error) for all endpoints measured in published studies. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, D. Jenkins-Hill, J. McCord, M. Strynar, L. Wehmas, S. Hester, D. Macmillan, and L. Gray. Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS). ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 160(107056): 1, (2022).
Conley 2023 Dose additive effects mixture HFPO-DA, NBP2, PFOS Dataset
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Dataset includes summary statistics (mean, standard error, sample size) for all endpoints measured and reported in the experiments described in the published manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, A. Farraj, J. Smoot, R. Grindstaff, D. Jenkins-Hill, J. McCord, E. Medlock Kakaley, A. Dixon, E. Hines, and L. Gray. Dose additive maternal and offspring effects of oral maternal exposure to a mixture of three PFAS (HFPO-DA, NBP2, PFOS) during pregnancy in the Sprague-Dawley rat. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 892: 164609, (2023).
Gupta 2025 Dipentyl phthalate testis dose response dataset
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Dataset includes summary data for all endpoints measured in the experiments reported in the manuscript. This dataset is associated with the following publication: GUPTA, M., J. Conley, C. Lambright, L. Chin, S. HILL, L. Gray, and D. SPADE. Dose-response assessment of dipentyl phthalate effects on testosterone production and morphogenesis of late-gestation fetal rat testis. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 200: 109551, (2025).
(Crit. Rev. Tox.) Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects
공공데이터포털
This paper uses EPA public data to build new datasets and analysis by non-EPA authors. This dataset is not publicly accessible because: Data was not collected in EPA labs or paid for by EPA. It can be accessed through the following means: This paper uses EPA public data to build new datasets and analysis by non-EPA authors. Format: N/A. This dataset is associated with the following publication: Theunissen, P., S. Beken, B. Beyer, W. Breslin, G. Cappon, C. Chen, G. Chmielewski, L. De Schaepdrijver, B. Enright, J. Foreman, W. Harrouk, K. Hew, A. Hoberman, J. Hui, T. Knudsen , S. Laffan, S. Makris , M. Martin , M. McNerney, C. Siezen, D. Stanislaus, J. Stewart, K. Thompson, B. Tornesi, G. Weinbauer, S. Wood, J. Van der Laan, and A. Piersma. (Crit. Rev. Tox.) Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects. CRITICAL REVIEWS IN TOXICOLOGY. CRC Press LLC, Boca Raton, FL, USA, 1-11, (2016).
(Crit. Rev. Tox.) Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects
공공데이터포털
This paper uses EPA public data to build new datasets and analysis by non-EPA authors. This dataset is not publicly accessible because: Data was not collected in EPA labs or paid for by EPA. It can be accessed through the following means: This paper uses EPA public data to build new datasets and analysis by non-EPA authors. Format: N/A. This dataset is associated with the following publication: Theunissen, P., S. Beken, B. Beyer, W. Breslin, G. Cappon, C. Chen, G. Chmielewski, L. De Schaepdrijver, B. Enright, J. Foreman, W. Harrouk, K. Hew, A. Hoberman, J. Hui, T. Knudsen , S. Laffan, S. Makris , M. Martin , M. McNerney, C. Siezen, D. Stanislaus, J. Stewart, K. Thompson, B. Tornesi, G. Weinbauer, S. Wood, J. Van der Laan, and A. Piersma. (Crit. Rev. Tox.) Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects. CRITICAL REVIEWS IN TOXICOLOGY. CRC Press LLC, Boca Raton, FL, USA, 1-11, (2016).
Transcriptomic data (GSE199233) and CEBs data (from Blake et al. 2020) for maternal and fetal endpoints following gestational exposure to PFOA or GenX
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Maternal and fetal liver gene expression and pathway changes following exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA) during gestation. This dataset is associated with the following publication: Blake, B., C. Miller, H. Nguyen, V. Chappell, T. Phan, D. Phadke, M. Balik-Meisner, D. Mav, R. Shah, and S. Fenton. Transcriptional pathways linked to fetal and maternal hepatic dysfunction caused by gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) in CD-1 mice. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. Elsevier Science Ltd, New York, NY, USA, 248: 114314, (2022).
DINP VS T PROD AND INSL3 DOSE RESPONSE 2023
공공데이터포털
DATA USED IN PAPER. This dataset is associated with the following publication: Gray, L. Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 465(116454): 1, (2023).
DINP VS T PROD AND INSL3 DOSE RESPONSE 2023
공공데이터포털
DATA USED IN PAPER. This dataset is associated with the following publication: Gray, L. Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 465(116454): 1, (2023).
Adverse maternal, fetal, and neonatal effects of GenX from oral gestational exposure in Sprague Dawley rats Dataset
공공데이터포털
Dataset contains summary data (mean, standard error, sample size (n)) for all measured endpoints reported and depicted in the corresponding manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, M. Strynar, J. McCord, B. McIntyre, G. Travlos, M. Cardon, E. MedlockKakaley, P. Hartig, V. Wilson, and E. Gray. Adverse maternal, fetal, and postnatal effects of Hexafluoropropylene oxide dimer acid (GenX) from oral gestational exposure in Sprague Dawley rats. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 1-13, (2019).
Adverse maternal, fetal, and neonatal effects of GenX from oral gestational exposure in Sprague Dawley rats Dataset
공공데이터포털
Dataset contains summary data (mean, standard error, sample size (n)) for all measured endpoints reported and depicted in the corresponding manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, M. Strynar, J. McCord, B. McIntyre, G. Travlos, M. Cardon, E. MedlockKakaley, P. Hartig, V. Wilson, and E. Gray. Adverse maternal, fetal, and postnatal effects of Hexafluoropropylene oxide dimer acid (GenX) from oral gestational exposure in Sprague Dawley rats. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 1-13, (2019).