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Gupta 2025 Dipentyl phthalate testis dose response dataset
Dataset includes summary data for all endpoints measured in the experiments reported in the manuscript. This dataset is associated with the following publication: GUPTA, M., J. Conley, C. Lambright, L. Chin, S. HILL, L. Gray, and D. SPADE. Dose-response assessment of dipentyl phthalate effects on testosterone production and morphogenesis of late-gestation fetal rat testis. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 200: 109551, (2025).
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Gray 2025 Phthalate transcriptomic and apical points of departure dataset
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Dataset includes all endpoint measurements from studies described in the manuscript and SAS code for statistical analyses of data. This dataset is associated with the following publication: Gray, L., C. Lambright, N. Evans, J. Ford, and J. Conley. Comparison of in utero phthalate exposure on fetal rat testis transcript and endocrine alterations with apical reproductive alterations in male rats. TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier B.V., Amsterdam, NETHERLANDS, 502: 117447, (2025).
dicyclohexyl phthalate fetal testis gene expression data
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dicyclohexyl phthalate fetal testis data
Phthalate Intakes
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Compilation of literature-reported intake values of phthalates; specifically dibutyl phthalate (DBP), bis(2-ethylhexyl) phthalate, and diisononyl phthalate (DiNP). This dataset is associated with the following publication: Moreau, M., J. Leonard, K. Phillips, J. Campbell, S. Pendse, C. Nicolas, M. Phillips, M. Yoon, C. Tan, S. Smith, H. Pudukodu, K. Isaacs, and H. Clewell. Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates. CHEMOSPHERE. Elsevier Science Ltd, New York, NY, USA, 184: 1194-1201, (2017).
Conley 2021 NBP2 Dev tox Dataset 2022-1-10.xlsx
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Dataset contains summary data (mean +/- error) for all endpoints measured in published studies. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, D. Jenkins-Hill, J. McCord, M. Strynar, L. Wehmas, S. Hester, D. Macmillan, and L. Gray. Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS). ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 160(107056): 1, (2022).
Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity
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R-language data files from "Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS, Henderson WM, Richard AM, Patlewicz G, Wetmore BA, Paul Friedman K, Shafer T. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. Chem Res Toxicol. 2023 Mar 20;36(3):402-419. doi: 10.1021/acs.chemrestox.2c00344. Epub 2023 Feb 23. PMID: 36821828.". This dataset is associated with the following publication: Carstens, K., T. Freudenrich, K. Wallace, S. Choo, A. Carpenter, M. Smeltz, M. Clifton, M. Henderson, A. Richard, G. Patlewicz, B. Wetmore, K. Friedman, and T. Shafer. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 36(3): 402-419, (2023).
Conley 2023 Dose additive effects mixture HFPO-DA, NBP2, PFOS Dataset
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Dataset includes summary statistics (mean, standard error, sample size) for all endpoints measured and reported in the experiments described in the published manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, A. Farraj, J. Smoot, R. Grindstaff, D. Jenkins-Hill, J. McCord, E. Medlock Kakaley, A. Dixon, E. Hines, and L. Gray. Dose additive maternal and offspring effects of oral maternal exposure to a mixture of three PFAS (HFPO-DA, NBP2, PFOS) during pregnancy in the Sprague-Dawley rat. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 892: 164609, (2023).
Effects of the diphenyl herbicide, oxyfluorfen, on thyroid hormones in the juvenile rat following 4- and 8-day exposure..
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Data on hormone and chemical analysis is included for the effects of oxyfluorfen on thyroid hormones in the 4- and 8-day exposed juvenile rats. This dataset is associated with the following publication: Stoker, T., G. DeVane, A. Buckalew, J. Bailey, J. Ford, and A. Murr. Evaluation of the diphenyl herbicide, Oxyfluorfen, for effects on thyroid hormones in the juvenile rat.. Current Research in Toxicology. Elsevier B.V., Amsterdam, NETHERLANDS, 6: 100146, (2023).
Dataset for A rapid assessment bioaccumulation screening (RABS) study design for emerging per-and polyfluoroalkyl substances in mice exposed to industrially impacted surface water
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All data tables are available in the publication and uploaded onto ScienceHub. This dataset is associated with the following publication: Bangma, J., T.C. Guillette, M. Strynar, A. Lindstrom, J. McCord, D. Jenkins-Hill, C. Lau, N. Chernoff, and J. Lang. A rapid assessment bioaccumulation screening (RABS) study design for emerging per-and polyfluoroalkyl substances in mice exposed to industrially impacted surface water. CHEMOSPHERE. Elsevier Science Ltd, New York, NY, USA, 308(1): 136159, (2022).
Data set for a PFAS pestilcide pyrifluquinazon + dibutyl phthalate in utero mixture on male rat offspring reproductive development. Dose Additive effects of dissimilarly acting toxicants
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data set has a description of the information in the excell file and all the data used in the study. This dataset is associated with the following publication: Gray, E., J. Conley, C. Lambright, and J. Furr. In utero exposure to a mixture of the perfluoroalkylisopropyl pesticide pyrifluquinazon with dibutyl phthalate cumulatively disrupts male rat reproductive development via different mechanisms of action. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(2): 234-247, (2022).
Establishing the “Biological Relevance” of Dipentyl Phthalate Reductions in Fetal Rat Testosterone Production and Plasma and Testis Testosterone Levels
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metadata sheet, data sheet for each table and figure in the published manuscript. This dataset is associated with the following publication: Gray , E., J. Furr , K. Tatum-Gibbs, C. Lambright , H. Sampson, B. Hannas, V. Wilson , A. Hotchkiss , and P. Foster. Establishing the Biological Relevance of Dipentyl Phthalate Reductions in Fetal Rat Testosterone Production and Plasma and Testis Testosterone Levels. TOXICOLOGICAL SCIENCES. Society of Toxicology, 149(1): 178-91, (2016).