This dataset provides exposure and effects data for two experiments regarding the dietborne toxicity of inorganic arsenic and selected organoarsenicals on rainbow trout survival and growth. There are separate spreadsheets for the two experiments, at the replicate exposure chamber level, of measured fish weights and survival and calculated growth metrics. Each spreadsheet provides footnote descriptions of the data and calculations provided. Descriptions of experimental protocols are also provided as supporting documents. This dataset is associated with the following publication: Erickson, R., D. Mount, T. Highland, R. Hockett, D. Hoff, C. Jenson, and T. Lahren. The effects of arsenic speciation on accumulation and toxicity of dietborne arsenic exposures to rainbow trout.. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 210: 227-241, (2019).

This dataset provides exposure and effects data for two experiments regarding the dietborne toxicity of inorganic arsenic on fathead minnows survival and growth. There are separate spreadsheets for the two experiments, at the replicate exposure chamber level, of fish exposure, survival, and weights and calculated growth metrics. Each spreadsheet provides footnote descriptions of the data and calculations provided. Descriptions of experimental protocols are also provided as supporting documents. This dataset is associated with the following publication: Erickson, R., D. Mount, T. Highland, R. Hockett, D. Hoff, C. Jenson, and T. Lahren. The relative importance of waterborne and dietborne As exposure on survival and growth of juvenile fathead minnows. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 211: 18-28, (2019).

Results of acute and chronic exposure of rainbow trout and warm water fish to metals and other toxicants.

Results of acute and chronic exposure of rainbow trout and warm water fish to metals and other toxicants.

Our research used a combination of laboratory-based acute aqueous metals exposures and RNA-sequencing technologies to identify a gene-based means to extrapolate metals toxicity across a range of fish taxa. For Phase 1 of our project, we compared transcriptome changes in caudal fin, gill and liver of juvenile Rainbow trout (Oncorhynchus mykiss) exposed to cadmium (Cd), copper (Cu), or zinc (Zn) at 17, or 50% of LC50 concentrations for 24 and 96 hours to controls. These experiments allowed us to test for conserved responses to the metal exposures, and to test which metal produced the most coherent gene expression profile indicative of a defined mode of action. During Phase 2, we exposed juvenile Chinook salmon (Oncorhynchus tshawytscha) to the selected metal (Zn) to begin to ascertain the extent to which the mode of action identified was conserved among salmonids.

Mouse assays. This dataset is associated with the following publication: Diamond, G., K. Bradham, and D. Thomas. Evaluating the Mouse Model for Estimation of Arsenic Bioavailability: Comparison of Estimates of Absolute Bioavailability of Inorganic Arsenic in Mouse, Humans, and Other Species. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, USA, 85(19): 815-825, (2022).

Linear combination fitting results of synchrotron data to determine arsenic speciation in soil samples. This dataset is associated with the following publication: Whitacre, S., N. Basta, B. Stevens, V. Hanley, R. Anderson, and K. Scheckel. Modification of an Existing In vitro Method to Predict Relative Bioavailable Arsenic in Soils. Jacob de Boer, and Shane Snyder CHEMOSPHERE. Elsevier Science Ltd, New York, NY, USA, 180: 545-552, (2017).

Linear combination fitting results of synchrotron data to determine arsenic speciation in soil samples. This dataset is associated with the following publication: Whitacre, S., N. Basta, B. Stevens, V. Hanley, R. Anderson, and K. Scheckel. Modification of an Existing In vitro Method to Predict Relative Bioavailable Arsenic in Soils. Jacob de Boer, and Shane Snyder CHEMOSPHERE. Elsevier Science Ltd, New York, NY, USA, 180: 545-552, (2017).

This dataset includes data collected to validate a method of analysis for arsenic species As(III), As(V), dimethylarsinate (DMA), and monomethylarsonate (MMA) in surface water and groundwater samples. It also includes site information and water chemistry for samples used in the validation and used for other studies of arsenic species in groundwater. It includes speciation data measured at multiple time points to establish or verify hold times and stability of As species in surface water and groundwater samples.

This dataset includes data collected to validate a method of analysis for arsenic species As(III), As(V), dimethylarsinate (DMA), and monomethylarsonate (MMA) in surface water and groundwater samples. It also includes site information and water chemistry for samples used in the validation and used for other studies of arsenic species in groundwater. It includes speciation data measured at multiple time points to establish or verify hold times and stability of As species in surface water and groundwater samples.