데이터셋 상세
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Dataset for Chemical Signatures of neurodevelopmental disorders
This dataset contains the data, code and associated files for the manuscript Authored by Marable et al. This dataset is associated with the following publication: Marable, C., C. Frank, R. Seim, S. Hester, M. Henderson, B. Chorley, and T. Shafer. Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated with Chemical Alterations of in vitro Neural Network Formation. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 186(1): 118-133, (2022).
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연관 데이터
Provides an overview of the analysis and associated files, scripts and datasets
공공데이터포털
This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the following publication: Ball, K., C. Grant, W. Mundy, and T. Shafer. A multivariate extension of mutual information for growing neural networks.. Neural Networks. Elsevier B.V., Amsterdam, NETHERLANDS, 95: 29-43, (2017).
Provides an overview of the analysis and associated files, scripts and datasets
공공데이터포털
This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the following publication: Ball, K., C. Grant, W. Mundy, and T. Shafer. A multivariate extension of mutual information for growing neural networks.. Neural Networks. Elsevier B.V., Amsterdam, NETHERLANDS, 95: 29-43, (2017).
Data for Brown et al MEA Developmental Neurotoxicity Screening Manuscript
공공데이터포털
These data are the individual parameter and well-level data that were support the conclusions in Brown et al. Note: the parameters CVtime and CVnetwork were not used. This dataset is associated with the following publication: Brown, J., D. Hall, C. Frank, K. Wallace, W. Mundy, and T. Shafer. Editor's highlight: Evaluation of a Microelectrode Array-based Assay for Neural Network Ontogeny using Training Set Chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, 154(1): 126-139, (2016).
Data for Tipping Point determinations
공공데이터포털
The attached zip file contains all of the source data, intermediate outputs and R-scripts used to calculate the tipping points reported in the Frank et al manuscript. This dataset is associated with the following publication: Christopher, F., J. Brown, K. Wallace, J. Wambaugh, I. Shah, and T. Shafer. Defining toxicological tipping points in neuronal network development. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 354: 81-93, (2018).
MEA 86 Compound data
공공데이터포털
This data file contains the full raw parameter data for the 86 compounds tested in the developmental MEA assay, as well as Area Under the Curve (AUC) calculations and plate normalized data.
Data for Harrill et al, Testing for developmental neurotoxicity using a suite of assays for key cellular events in neurodevelopment
공공데이터포털
This file contains the data on apoptosis, neurite outgrowth, synaptogenesis and proliferation. This dataset is associated with the following publication: Harrill, J., T. Freudenrich, K. Wallace, K. Ball, T. Shafer, and W. Mundy. Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 354(1): 24-39, (2018).
KodavantiP-Acute HSAB AOP Neurotox Science Hub Data 090319
공공데이터포털
Neurotox data on in silico predicted chemicals to cause protein adducts in peripheral neurons. Includes cytotoxicity (LDH release), changes in neuron network architecture using high content imaging and neurophysiology via microelectrode arrays. This dataset is associated with the following publication: Johnstone, A., C. Mack, M. Valdez, T. Shafer, D. Herr, P. Kodavanti, and R. Lo Pachin. Acute In Vitro Effects on Embryonic Rat Dorsal Root Ganglion (DRG) Cultures by In Silico Predicted Neurotoxic Chemicals: Evaluations on Cytotoxicity, Neurite Length, and Neurophysiology.. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 69(104989): 1, (2020).
Moser NTT 52:2015
공공데이터포털
data supporting manuscript figures. This dataset is associated with the following publication: Moser , V.C., P. Phillips , J. Hedge , and K. Mcdaniel. Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDICPP) and tris(2-chloro-2-ethyl)phosphate(TCEP). NEUROTOXICOLOGY AND TERATOLOGY. Elsevier Science Ltd, New York, NY, USA, 52: 236-247, (2015).
Moser NTT 52:2015
공공데이터포털
data supporting manuscript figures. This dataset is associated with the following publication: Moser , V.C., P. Phillips , J. Hedge , and K. Mcdaniel. Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDICPP) and tris(2-chloro-2-ethyl)phosphate(TCEP). NEUROTOXICOLOGY AND TERATOLOGY. Elsevier Science Ltd, New York, NY, USA, 52: 236-247, (2015).
Scientific journal article
공공데이터포털
Files associated with the manuscript: Proteome profiling of rat brain cortical changes during early postnatal brain development. This dataset is associated with the following publication: Winnik, W., W. Padgett, E. Pitzer, and D. Herr. Proteome profiling of rat brain cortical changes during early postnatal brain development. Journal of Proteome Research. American Chemical Society, Washington, DC, USA, 22(7): 2460-2476, (2023).