Data set for Vassallo et al

공공데이터포털

The dataset contains data from MEA recordings for 6 different compounds that were tested in a concentration-response format. Multiple parameters of neural network function were evaluated. This dataset is associated with the following publication: Shafer , T., C. Mack , A. Johnstone , A. Vassallo, M. Chiappalone, R. De Camargo Lopes, B. Scelfo, A. Novellino, E. Defranchi, T. Palosaari, T. Weisschu, T. Ramirez, R. Landsiedel, S. Martinoia, M. Whealan, and A. Bal-Price. A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.. NEUROTOXICOLOGY. Elsevier B.V., Amsterdam, NETHERLANDS, 60: 280-292, (2017).

Data set for Vassallo et al

공공데이터포털

The dataset contains data from MEA recordings for 6 different compounds that were tested in a concentration-response format. Multiple parameters of neural network function were evaluated. This dataset is associated with the following publication: Shafer , T., C. Mack , A. Johnstone , A. Vassallo, M. Chiappalone, R. De Camargo Lopes, B. Scelfo, A. Novellino, E. Defranchi, T. Palosaari, T. Weisschu, T. Ramirez, R. Landsiedel, S. Martinoia, M. Whealan, and A. Bal-Price. A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.. NEUROTOXICOLOGY. Elsevier B.V., Amsterdam, NETHERLANDS, 60: 280-292, (2017).

Provides an overview of the analysis and associated files, scripts and datasets

공공데이터포털

This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the following publication: Ball, K., C. Grant, W. Mundy, and T. Shafer. A multivariate extension of mutual information for growing neural networks.. Neural Networks. Elsevier B.V., Amsterdam, NETHERLANDS, 95: 29-43, (2017).

Provides an overview of the analysis and associated files, scripts and datasets

공공데이터포털

This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the following publication: Ball, K., C. Grant, W. Mundy, and T. Shafer. A multivariate extension of mutual information for growing neural networks.. Neural Networks. Elsevier B.V., Amsterdam, NETHERLANDS, 95: 29-43, (2017).

NHEERL MEA Toxcast Single Concentration Screening data

공공데이터포털

This file contains the data used to generate hit calls from neural activity recordings on microelectrode array (MEA) plates treated with ToxCast compounds at a single concentration. This dataset is associated with the following publication: Strickland, J., M. Martin, A. Richard, K. Houck, and T. Shafer. Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates. Archives of Toxicology. Springer, New York, NY, USA, 92(1): 487-500, (2018).

NHEERL MEA Toxcast Single Concentration Screening data

공공데이터포털

This file contains the data used to generate hit calls from neural activity recordings on microelectrode array (MEA) plates treated with ToxCast compounds at a single concentration. This dataset is associated with the following publication: Strickland, J., M. Martin, A. Richard, K. Houck, and T. Shafer. Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates. Archives of Toxicology. Springer, New York, NY, USA, 92(1): 487-500, (2018).

Data for Tipping Point determinations

공공데이터포털

The attached zip file contains all of the source data, intermediate outputs and R-scripts used to calculate the tipping points reported in the Frank et al manuscript. This dataset is associated with the following publication: Christopher, F., J. Brown, K. Wallace, J. Wambaugh, I. Shah, and T. Shafer. Defining toxicological tipping points in neuronal network development. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 354: 81-93, (2018).

Data for Tipping Point determinations

공공데이터포털

The attached zip file contains all of the source data, intermediate outputs and R-scripts used to calculate the tipping points reported in the Frank et al manuscript. This dataset is associated with the following publication: Christopher, F., J. Brown, K. Wallace, J. Wambaugh, I. Shah, and T. Shafer. Defining toxicological tipping points in neuronal network development. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 354: 81-93, (2018).

Data for Brown et al MEA Developmental Neurotoxicity Screening Manuscript

공공데이터포털

These data are the individual parameter and well-level data that were support the conclusions in Brown et al. Note: the parameters CVtime and CVnetwork were not used. This dataset is associated with the following publication: Brown, J., D. Hall, C. Frank, K. Wallace, W. Mundy, and T. Shafer. Editor's highlight: Evaluation of a Microelectrode Array-based Assay for Neural Network Ontogeny using Training Set Chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, 154(1): 126-139, (2016).

Data for Brown et al MEA Developmental Neurotoxicity Screening Manuscript

공공데이터포털

These data are the individual parameter and well-level data that were support the conclusions in Brown et al. Note: the parameters CVtime and CVnetwork were not used. This dataset is associated with the following publication: Brown, J., D. Hall, C. Frank, K. Wallace, W. Mundy, and T. Shafer. Editor's highlight: Evaluation of a Microelectrode Array-based Assay for Neural Network Ontogeny using Training Set Chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, 154(1): 126-139, (2016).