NHEERL MEA Toxcast Single Concentration Screening data

공공데이터포털

This file contains the data used to generate hit calls from neural activity recordings on microelectrode array (MEA) plates treated with ToxCast compounds at a single concentration. This dataset is associated with the following publication: Strickland, J., M. Martin, A. Richard, K. Houck, and T. Shafer. Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates. Archives of Toxicology. Springer, New York, NY, USA, 92(1): 487-500, (2018).

Data set for Kosnik et al

공공데이터포털

The zip file contains all data and scripts used for the material presented in the manuscript by Kosnik et al. This dataset is associated with the following publication: Kosnik, M., J. Strickland, S. Marvel, D. Wallis, K. Wallace, A. Richard, D. Reif, and T. Shafer. Concentration-Response Evaluation of ToxCast Compounds for Multivariate Activity Patterns of Neural Network Function. Archives of Toxicology. Springer, New York, NY, USA, 94: 469-484, (2020).

Data set for Kosnik et al

공공데이터포털

The zip file contains all data and scripts used for the material presented in the manuscript by Kosnik et al. This dataset is associated with the following publication: Kosnik, M., J. Strickland, S. Marvel, D. Wallis, K. Wallace, A. Richard, D. Reif, and T. Shafer. Concentration-Response Evaluation of ToxCast Compounds for Multivariate Activity Patterns of Neural Network Function. Archives of Toxicology. Springer, New York, NY, USA, 94: 469-484, (2020).

Data set for Vassallo et al

공공데이터포털

The dataset contains data from MEA recordings for 6 different compounds that were tested in a concentration-response format. Multiple parameters of neural network function were evaluated. This dataset is associated with the following publication: Shafer , T., C. Mack , A. Johnstone , A. Vassallo, M. Chiappalone, R. De Camargo Lopes, B. Scelfo, A. Novellino, E. Defranchi, T. Palosaari, T. Weisschu, T. Ramirez, R. Landsiedel, S. Martinoia, M. Whealan, and A. Bal-Price. A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.. NEUROTOXICOLOGY. Elsevier B.V., Amsterdam, NETHERLANDS, 60: 280-292, (2017).

Data set for Vassallo et al

공공데이터포털

The dataset contains data from MEA recordings for 6 different compounds that were tested in a concentration-response format. Multiple parameters of neural network function were evaluated. This dataset is associated with the following publication: Shafer , T., C. Mack , A. Johnstone , A. Vassallo, M. Chiappalone, R. De Camargo Lopes, B. Scelfo, A. Novellino, E. Defranchi, T. Palosaari, T. Weisschu, T. Ramirez, R. Landsiedel, S. Martinoia, M. Whealan, and A. Bal-Price. A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.. NEUROTOXICOLOGY. Elsevier B.V., Amsterdam, NETHERLANDS, 60: 280-292, (2017).

MEA 86 Compound data

공공데이터포털

This data file contains the full raw parameter data for the 86 compounds tested in the developmental MEA assay, as well as Area Under the Curve (AUC) calculations and plate normalized data.

MEA 86 Compound data

공공데이터포털

This data file contains the full raw parameter data for the 86 compounds tested in the developmental MEA assay, as well as Area Under the Curve (AUC) calculations and plate normalized data.

Provides an overview of the analysis and associated files, scripts and datasets

공공데이터포털

This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the following publication: Ball, K., C. Grant, W. Mundy, and T. Shafer. A multivariate extension of mutual information for growing neural networks.. Neural Networks. Elsevier B.V., Amsterdam, NETHERLANDS, 95: 29-43, (2017).

Provides an overview of the analysis and associated files, scripts and datasets

공공데이터포털

This dataset contains the files, scripts and data that were used to run the simulations and data analyses for the manuscript. This dataset is associated with the following publication: Ball, K., C. Grant, W. Mundy, and T. Shafer. A multivariate extension of mutual information for growing neural networks.. Neural Networks. Elsevier B.V., Amsterdam, NETHERLANDS, 95: 29-43, (2017).

Dataset for Saavedra et al.

공공데이터포털

Data in each figure of the publication are provided in different tabs of the excel spreadsheet. There were multiple concentrations tested, which are listed in the rows of the sheet. Each column is a different replicate. This dataset is associated with the following publication: Saavedra, L., K. Wallace, T. Freudenrich, M. Mall, W. Mundy, J. Davila, T. Shafer, M. Wernig, and D. Haag. Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 180(2): 295-312, (2021).