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Epigenetic effects of ozone in the rodent lung
Pulmonary gene expression related to the regulation of DNA methylation following an exposure to ozone in rats. Epigenetic regulation of a pulmonary hypertensive gene, apelin, was also quantified. This dataset is associated with the following publication: Miller, C., J. Dye, M. Schladweiler, J. Richards, A. Ledbetter, E. Stewart, and U. Kodavanti. Acute inhalation of ozone induces DNA methylation of apelin in lungs of Long-Evans rats.. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 30(4): 178-186, (2018).
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In Vitro Ozone Responsiveness Data
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Data collected during the comparison of ozone responsiveness in primary bronchial epithelial cells from a range of distinct donors. This dataset is associated with the following publication: Bowers, E., S. McCullough, D. Morgan, L. Dailey, and D. Diaz-Sanchez. ERK1/2 and p38 regulate inter-individual variability in ozone-mediated IL-8 gene expression in primary human bronchial epithelial cells. Scientific Reports. Nature Publishing Group, London, UK, 8(1): 9398, (2018).
In Vitro Ozone Responsiveness Data
공공데이터포털
Data collected during the comparison of ozone responsiveness in primary bronchial epithelial cells from a range of distinct donors. This dataset is associated with the following publication: Bowers, E., S. McCullough, D. Morgan, L. Dailey, and D. Diaz-Sanchez. ERK1/2 and p38 regulate inter-individual variability in ozone-mediated IL-8 gene expression in primary human bronchial epithelial cells. Scientific Reports. Nature Publishing Group, London, UK, 8(1): 9398, (2018).
Ozone-Lung-Path
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Data related to Dye et al pub on ozone and lung pathology. This dataset is associated with the following publication: Dye, J., H. Nguyen, E. Stewart, M. Schladweiler, and C. Miller. Sex differences in impacts of early gestational and peri-adolescent ozone exposure on lung development in rats: Implications for later life disease in humans. AMERICAN JOURNAL OF PATHOLOGY. American Association of Pathologist, 194(9): 1636-1663, (2024).
Exacerbation of ozone-induced pulmonary and systemic effects by 2-adrenergic and/or glucocorticoid agonist/s
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This data set pertains to the manuscript "Exacerbation of ozone-induced pulmonary and systemic effects by 2-adrenergic and/or glucocorticoid agonist/s". It shows the raw data for each figure in the manuscript that is created with these data. Basically examining the influence of beta adrenergic and glucocorticoid receptor agonists on ozone-induced lung injury and inflammation. This dataset is associated with the following publication: Henriquez, A., S. Snow, M. Schladweiler, C. Miller, J. Dye, A. Ledbetter, M. Hargrove, U. Kodavanti, and J. Richards. Exacerbation of ozone-induced pulmonary and systemic effects by beta2-adrenergic and/or glucocorticoid agonist/s. Scientific Reports. Nature Publishing Group, London, UK, 9(1): 17925, (2019).
Ozone-induced systemic and pulmonary effects are diminished in adrenalectomized rats
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This data set is an excel file pertaining to the study that examined ozone-induced systemic and pulmonary effects in rats that underwent SHAM surgery (control), adrenal demedullation or total bilateral adrenalectomy. Different pages of the spreadsheet shows individual animal data for markers of lung injury and inflammation, body weights, whole body plethysmography measurements, levels of circulating hormones and lipids, and circulating white blood cell count as well as platelet count. This dataset is associated with the following publication: Miller, D., S. Snow, M. Schladweiler , J. Richards , A. Ghio , A. Ledbetter , and U. Kodavanti. Acute Ozone-Induced Pulmonary and Systemic Metabolic Effects are Diminished in Adrenalectomized Rats#. TOXICOLOGICAL SCIENCES. Society of Toxicology, 150(2): 312-22, (2016).
Ozone-induced systemic and pulmonary effects are diminished in adrenalectomized rats
공공데이터포털
This data set is an excel file pertaining to the study that examined ozone-induced systemic and pulmonary effects in rats that underwent SHAM surgery (control), adrenal demedullation or total bilateral adrenalectomy. Different pages of the spreadsheet shows individual animal data for markers of lung injury and inflammation, body weights, whole body plethysmography measurements, levels of circulating hormones and lipids, and circulating white blood cell count as well as platelet count. This dataset is associated with the following publication: Miller, D., S. Snow, M. Schladweiler , J. Richards , A. Ghio , A. Ledbetter , and U. Kodavanti. Acute Ozone-Induced Pulmonary and Systemic Metabolic Effects are Diminished in Adrenalectomized Rats#. TOXICOLOGICAL SCIENCES. Society of Toxicology, 150(2): 312-22, (2016).
Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats
공공데이터포털
This data set provides the biological endpoints collected from individual animals that culminated into a published paper. This dataset is associated with the following publication: Snow, S., C. Gordon , V. Bass, M. Schladweiler , A. Ledbetter , K. Jarema , P. Phillips , A. Johnstone , and U. Kodavanti. Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats. INHALATION TOXICOLOGY. Informa Healthcare USA, New York, NY, USA, 28(7): 313-23, (2016).
Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats
공공데이터포털
This data set provides the biological endpoints collected from individual animals that culminated into a published paper. This dataset is associated with the following publication: Snow, S., C. Gordon , V. Bass, M. Schladweiler , A. Ledbetter , K. Jarema , P. Phillips , A. Johnstone , and U. Kodavanti. Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats. INHALATION TOXICOLOGY. Informa Healthcare USA, New York, NY, USA, 28(7): 313-23, (2016).
Corteselli et al Ozone PUFA Ox Stress
공공데이터포털
These are the data for the figures in the manuscript. This dataset is associated with the following publication: Corteselli, E., A. Gold, J. Surratt, T. Cui, P. Bromberg, L. Dailey, and J. Samet. Supplementation with Omega-3 Fatty Acids Potentiates Oxidative Stress in Human Airway Epithelial Cells Exposed to Ozone. ENVIRONMENTAL RESEARCH. Elsevier B.V., Amsterdam, NETHERLANDS, 187: 109627, (2020).
Corteselli et al Ozone PUFA Ox Stress
공공데이터포털
These are the data for the figures in the manuscript. This dataset is associated with the following publication: Corteselli, E., A. Gold, J. Surratt, T. Cui, P. Bromberg, L. Dailey, and J. Samet. Supplementation with Omega-3 Fatty Acids Potentiates Oxidative Stress in Human Airway Epithelial Cells Exposed to Ozone. ENVIRONMENTAL RESEARCH. Elsevier B.V., Amsterdam, NETHERLANDS, 187: 109627, (2020).
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