Epigenetic effects of ozone in the rodent lung

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Pulmonary gene expression related to the regulation of DNA methylation following an exposure to ozone in rats. Epigenetic regulation of a pulmonary hypertensive gene, apelin, was also quantified. This dataset is associated with the following publication: Miller, C., J. Dye, M. Schladweiler, J. Richards, A. Ledbetter, E. Stewart, and U. Kodavanti. Acute inhalation of ozone induces DNA methylation of apelin in lungs of Long-Evans rats.. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 30(4): 178-186, (2018).

Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats

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This data set provides the biological endpoints collected from individual animals that culminated into a published paper. This dataset is associated with the following publication: Snow, S., C. Gordon , V. Bass, M. Schladweiler , A. Ledbetter , K. Jarema , P. Phillips , A. Johnstone , and U. Kodavanti. Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats. INHALATION TOXICOLOGY. Informa Healthcare USA, New York, NY, USA, 28(7): 313-23, (2016).

Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats

공공데이터포털

This data set provides the biological endpoints collected from individual animals that culminated into a published paper. This dataset is associated with the following publication: Snow, S., C. Gordon , V. Bass, M. Schladweiler , A. Ledbetter , K. Jarema , P. Phillips , A. Johnstone , and U. Kodavanti. Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats. INHALATION TOXICOLOGY. Informa Healthcare USA, New York, NY, USA, 28(7): 313-23, (2016).

Exacerbation of ozone-induced pulmonary and systemic effects by 2-adrenergic and/or glucocorticoid agonist/s

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This data set pertains to the manuscript "Exacerbation of ozone-induced pulmonary and systemic effects by 2-adrenergic and/or glucocorticoid agonist/s". It shows the raw data for each figure in the manuscript that is created with these data. Basically examining the influence of beta adrenergic and glucocorticoid receptor agonists on ozone-induced lung injury and inflammation. This dataset is associated with the following publication: Henriquez, A., S. Snow, M. Schladweiler, C. Miller, J. Dye, A. Ledbetter, M. Hargrove, U. Kodavanti, and J. Richards. Exacerbation of ozone-induced pulmonary and systemic effects by beta2-adrenergic and/or glucocorticoid agonist/s. Scientific Reports. Nature Publishing Group, London, UK, 9(1): 17925, (2019).

Corteselli et al Ozone PUFA Ox Stress

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These are the data for the figures in the manuscript. This dataset is associated with the following publication: Corteselli, E., A. Gold, J. Surratt, T. Cui, P. Bromberg, L. Dailey, and J. Samet. Supplementation with Omega-3 Fatty Acids Potentiates Oxidative Stress in Human Airway Epithelial Cells Exposed to Ozone. ENVIRONMENTAL RESEARCH. Elsevier B.V., Amsterdam, NETHERLANDS, 187: 109627, (2020).

Corteselli et al Ozone PUFA Ox Stress

공공데이터포털

These are the data for the figures in the manuscript. This dataset is associated with the following publication: Corteselli, E., A. Gold, J. Surratt, T. Cui, P. Bromberg, L. Dailey, and J. Samet. Supplementation with Omega-3 Fatty Acids Potentiates Oxidative Stress in Human Airway Epithelial Cells Exposed to Ozone. ENVIRONMENTAL RESEARCH. Elsevier B.V., Amsterdam, NETHERLANDS, 187: 109627, (2020).

In Vitro Ozone Responsiveness Data

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Data collected during the comparison of ozone responsiveness in primary bronchial epithelial cells from a range of distinct donors. This dataset is associated with the following publication: Bowers, E., S. McCullough, D. Morgan, L. Dailey, and D. Diaz-Sanchez. ERK1/2 and p38 regulate inter-individual variability in ozone-mediated IL-8 gene expression in primary human bronchial epithelial cells. Scientific Reports. Nature Publishing Group, London, UK, 8(1): 9398, (2018).

In Vitro Ozone Responsiveness Data

공공데이터포털

Data collected during the comparison of ozone responsiveness in primary bronchial epithelial cells from a range of distinct donors. This dataset is associated with the following publication: Bowers, E., S. McCullough, D. Morgan, L. Dailey, and D. Diaz-Sanchez. ERK1/2 and p38 regulate inter-individual variability in ozone-mediated IL-8 gene expression in primary human bronchial epithelial cells. Scientific Reports. Nature Publishing Group, London, UK, 8(1): 9398, (2018).

ScienceHub file for multi-tissue transcriptomic and metabolomic response to inhaled ozone

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These data are published in a manuscript entitled Multi-tissue transcriptomic and serum metabolomic assessment reveals systemic implications of acute ozone-induced stress response in male Wistar Kyoto rats in the journal Metabolomics. This analyses explored systemic transcriptomic and circulating metabolomic effects of inhaled ozone exposure in rats. This dataset is associated with the following publication: Jackson, T., J. House, A. Henriquez, M. Schladweiler, K.M. Jackson, A. Astriab Fisher, S. Snow , D. Alewel, A. Motsinger-Reif, and U. Kodavanti. Multi-tissue transcriptomic and serum metabolomic assessment reveals systemic implications of acute ozone-induced stress response in male Wistar Kyoto rats. Metabolomics. Plenum Press, New York, NY, USA, 19: 81, (2023).

Ozone and IUGR CMiller

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Data related to the effects of peri-implantation ozone exposure on maternal and fetal health outcomes at the end of gestation. This dataset is associated with the following publication: Miller, C., J. Dye, A. Ledbetter, M. Schladweiler, J. Richards, S. Snow, C. Wood, A. Henriquez, L. Thompson, A. Farraj, M. Hazari, and U. Kodavanti. Uterine Artery Flow and Offspring Growth in Long-Evans Rats following Maternal Exposure to Ozone during Implantation. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 125(12): 127005, (2017).