Data from which figures and table in "A Model for Risk-Based Screening and Prioritization of Human Exposure to Chemicals from Near-Field Sources" were constructed. This dataset is associated with the following publication: Li, L., J. Westgate, L. Hughes, X. Zhang, B. Givehchi, L. Toose, J. Armitage, F. Wania, P. Egeghy, and J. Arnot. A Model for Risk-Based Screening and Prioritization of Human Exposure to Chemicals from Near-Field Sources. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 52(24): 14235-14244, (2018).

Dermal absorption is an important route of exposure that includes pharmaceuticals, consumer products and occupational exposures. "httk" is being developed as a tool to predict internal dose after exposure. The dermal route will be added to this package in order to account for dermal exposure. This dataset is associated with the following publication: Evans, M., T. Moxon, G. Lian, B. Deacon, T. Chen, L. Adams, A. Meade, and J. Wambaugh. A regression analysis using simple descriptors for multiple dermal datasets: Going from individual membranes to the full skin. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 43(6): 940-950, (2023).

Background information for human health margin of exposure paper. This dataset is associated with the following publication: Benson , B., O. Conerly , W. Sander, A. Batt , E. Furlong, S. Glassmeyer , D. Koplin, H. Mash , K. Schenck , J. Simmons , and S. Boone. Human Health Screening and Public Health Significance of Contaminants of Emerging Concern Detected in Public Water Supplies. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 579: 1643-1648, (2017).

Background information for human health margin of exposure paper. This dataset is associated with the following publication: Benson , B., O. Conerly , W. Sander, A. Batt , E. Furlong, S. Glassmeyer , D. Koplin, H. Mash , K. Schenck , J. Simmons , and S. Boone. Human Health Screening and Public Health Significance of Contaminants of Emerging Concern Detected in Public Water Supplies. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 579: 1643-1648, (2017).

Appendix Skin sensitization data and non‐animal test data for 271 chemicals. This dataset is associated with the following publication: Roberts, D., and G. Patlewicz. Non‐animal assessment of skin sensitization hazard: Is an integrated testing strategy needed, and if so what should be integrated?. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 38(1): 41-50, (2017).

Description is included in the dataset. This dataset is associated with the following publication: Daiber, E., D. DeMarini , S. Ravuri, H. Liberatore, A. Cuthbertson, A. Thompson-Klemish, J. Byer, J. Schmid , M. Afifi, E. Blatchley, and S. Richardson. Progressive Increase in Disinfection Byproducts and Mutagenicity from Sourceto Tap to Swimming Pool and Spa Water: Implications for Public Health. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 50(13): 6652-6662, (2016).

List of chemicals used for model evaluation, their MW, log KOW, and references for the original data source(s), the review(s) the data was collected from, and reference for log KOW as cited in the reviews. [Table SI-3 of research article]. This dataset is associated with the following publication: Brown, T., J. Armitage, P. Egeghy, I. Kircanski, and J. Arnot. Dermal permeation data and models for the prioritization and screening-level exposure assessment of organic chemicals. ENVIRONMENT INTERNATIONAL. Elsevier Science Ltd, New York, NY, USA, 94: 424-435, (2016).

This data release contains concentration and quality-assurance results for inorganic, organic analytes and microbiological pathogens collected from 30 different commercial bottled water sources. Samples were processed on July 20 and August 17, 2020 at the New Jersey Water Science Center and analyzed at various U.S. Geological Survey laboratories. Samples were analyzed for nutrients, cations and anions, trace elements and rare earth elements (REE) at the Redox Chemistry Laboratory and Analytical Trace Element Chemistry Laboratory in Boulder, Colorado; pharmaceutical, pesticide, per- and polyfluoroalkyl substances and volatile organic compounds at the National Water Quality Laboratory, Denver, Colorado; disinfection byproducts at the Organic Chemistry Research Laboratory, Sacramento, California; and microbiology at the Environmental and Public Health Microbiology Laboratory, St. Petersburg, Florida and Michigan Bacteriological Research Laboratory, Lansing, Michigan.

The data is on 4 tabs, separated by species (rat, human) and chemical (EH-TBB and BEH_TEBP). The data is by cell (2-4/skin), and includes %dose in receptor fluid over time, % unabsorbed, % absorbed and % penetrated. This dataset is associated with the following publication: Knudsen, G., M. Hughes, J.M. Sanders, S. Hall, and L. Birnbaum. Estimation of human percutaneous bioavailability for two novel brominated flame retardants, 2-ethylhexyl tetrabromobenzoate (EH-TBB) and bis(2-ethylhexyl) tetrabromophthalate (BEH-TEBP), using the parallelogram approach. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 311: 117-127, (2016).