EPA?s Integrated Risk Information System (IRIS) is a compilation of electronic reports on specific substances found in the environment and their potential to cause human health effects.

The High Production Volume Information System (HPVIS) provides access to select health and environmental effect information on chemicals that are manufactured in exceptionally large amounts.

The Acute Exposure Guideline Levels Chemical Listing provides a complete listing of risk exposure guidelines from rare exposure to certain chemicals.

The Distributed Structure-Searchable Toxicity (DSSTox) Database Network provides a public forum for search and publishing downloadable, structure-searchable, standardized chemical structure files associated with toxicity data.

The Distributed Structure-Searchable Toxicity (DSSTox) Database Network provides a public forum for search and publishing downloadable, structure-searchable, standardized chemical structure files associated with toxicity data.

This tool is intended to aid individuals interested in learning more about chemicals that are manufactured or imported into the United States. Health and safety information on these chemicals, primarily in the form of paper documents, are routinely submitted by industry (manufacturers or importers of chemicals) to EPA under the Toxic Substances Control Act (TSCA). EPA is in the process of converting these documents into electronic form and making non-confidential versions of these documents accessible through this tool. The tool enables users to conduct both full text and metadata searches of these documents, and presents these as .pdf for viewing or downloading. The tool also queries existing EPA legacy database sources of chemical information and presents these data in a consistent format.

Datasets for "A harmonized chemical monitoring database for support of exposure assessments". This dataset is associated with the following publication: Isaacs, K., J. Wall, A. Williams, K. Hobbie, J. Sobus, E. Ulrich, D. Lyons, K. Dionisio, A. Williams, C. Grulke, C. Foster, J. McCoy, and C. Bevington. A harmonized chemical monitoring database for support of exposure assessments. Scientific Data. Springer Nature, New York, NY, 9: 314, (2022).

The Consolidated Human Activity Database (CHAD) contains data obtained from human activity studies that were collected at city, state, and national levels. CHAD is intended to be an input file for exposure/intake dose modeling and/or statistical analysis.