Vector Alignment Search Tool (VAST)

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A computer algorithm that identifies similar protein 3-dimensional structures. Structure neighbors for every structure in MMDB are pre-computed and accessible via links on the MMDB Structure Summary pages.

Structure - Molecular Modeling Database (MMDB)

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Three dimensional structures provide a wealth of information on the biological function and the evolutionary history of macromolecules. They can be used to examine sequence-structure-function relationships, interactions, active sites, and more.

Protein

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The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. Protein sequences are the fundamental determinants of biological structure and function.

Medical Text Indexer (MTI)

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A system for producing indexing recommendations to assist in the indexing process at NLM. Currently provides indexing recommendations to more than 100 journals based on the NLM Medical Subject Headings (MeSH) vocabulary. MTI is the main product of the Indexing Initiative project and has been providing indexing recommendations based on the Medical Subject Headings (MeSH®) vocabulary since 2002. In 2011, NLM expanded MTI's role by designating it as the first-line indexer (MTIFL) for a few journals; today the MTIFL workflow includes over 350 journals and continues to increase. The close collaboration of the NLM Index Section, Lister Hill National Center for Biomedical Communications, and Office of Computer & Communications Systems continues to expand and refine the ability of MTI to provide assistance to the indexers.

Journal Article Tag Suite (JATS)

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Journal Article Tag Suite (JATS) is an application of NISO Z39.96.2019, which defines a set of XML elements and attributes for describing the textual and graphical content of journal articles and describes three article models.

MetaMap

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MetaMap is a highly configurable application developed by the Lister Hill National Center for Biomedical Communications at the National Library of Medicine (NLM) to map biomedical text to the UMLS Metathesaurus or, equivalently, to identify Metathesaurus concepts referred to in English text. MetaMap employs a knowledge-intensive approach, natural-language processing (NLP), and computational-linguistic techniques, and is used worldwide in industry and academia. At NLM, MetaMap is one of the foundations of NLM's Medical Text Indexer (MTI), which is applied to both semiautomatic and fully automatic indexing of biomedical literature. Technical documentation at http://metamap.nlm.nih.gov/#Downloads

RxMix

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An interface for building applications that allows users to combine functions of various NLM drug APIs, including the RxNorm, RxClass, RxTerms, and NDF-RT APIs. Sequences of functions can be executed interactively or in batch mode.

Transcriptome Shotgun Assembly (TSA) Sequence Database and Submissions

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TSA is an archive of computationally assembled transcript sequences from primary data such as ESTs and Next Generation Sequencing Technologies. The overlapping sequence reads from a complete transcriptome are assembled into transcripts by computational methods instead of by traditional cloning and sequencing of cloned cDNAs. The primary sequence data used in the assemblies must have been experimentally determined by the same submitter. TSA sequence records differ from GenBank records because there are no physical counterparts to the assemblies.

Aggregation Service

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,Collect and combine data from multiple internal and external data sources for exposure to consumers. Data for any individual is made available via a standard set of hierarchical HTTP resources through the Read Service. The VRS calls the ISIC external Producer endpoints to fetch and aggregate Care Coordinator Profiles VLER document type data and convert it to an XML Atom feed format for the Consumer.,

UMLS

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The Unified Medical Language System integrates and distributes key terminology, classification, and coding standards to promote interoperability