The dataset contains ambient air pollution data and circulating miRNA data of subjects from the CADEE study. This dataset is associated with the following publication: Chen, H., Y. Xu, A. Rappold, D. Diaz-Sanchez, and H. Tong. Effects of ambient ozone exposure on circulating extracellular vehicle microRNA levels in coronary artery disease patients. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, USA, 83(9): 351-362, (2020).

This dataset contains data of blood miRNA, cardiovascular biomarkers (i.e. inflammation, coagulation, and blood lipids), omega-3 index levels, as well as ambient PM2.5, O3 and NO2 concentrations from the panel study "PISCES". This dataset is associated with the following publication: Chen, H., S. Zhang, B. Yu, Y. Xu, A. Rappold, D. Diaz-Sanchez, J. Samet, and H. Tong. Circulating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. Elsevier Science Ltd, New York, NY, USA, 239(113604): 1, (2022).

Pulmonary gene expression related to the regulation of DNA methylation following an exposure to ozone in rats. Epigenetic regulation of a pulmonary hypertensive gene, apelin, was also quantified. This dataset is associated with the following publication: Miller, C., J. Dye, M. Schladweiler, J. Richards, A. Ledbetter, E. Stewart, and U. Kodavanti. Acute inhalation of ozone induces DNA methylation of apelin in lungs of Long-Evans rats.. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 30(4): 178-186, (2018).

These are the data for the figures in the manuscript. This dataset is associated with the following publication: Corteselli, E., A. Gold, J. Surratt, T. Cui, P. Bromberg, L. Dailey, and J. Samet. Supplementation with Omega-3 Fatty Acids Potentiates Oxidative Stress in Human Airway Epithelial Cells Exposed to Ozone. ENVIRONMENTAL RESEARCH. Elsevier B.V., Amsterdam, NETHERLANDS, 187: 109627, (2020).

This dataset contains a summary of compounds found in human blood samples. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding living individuals, according to the Privacy Act and the Freedom of Information Act (FOIA). This dataset contains information about human research subjects. Because there is potential to identify individual participants and disclose personal information, either alone or in combination with other datasets, individual level data are not appropriate to post for public access. Restricted access may be granted to authorized persons by contacting the party listed. It can be accessed through the following means: The analyzed data cannot be made publicly available. Format: The original dataset contains identification information for the sample subjects and all of their descriptors including age, gender, race, and medical screening information. The analyzed data cannot be made publicly available. This dataset is associated with the following publication: Stiegel, M., J. Pleil , J. Sobus , and M. Madden. Inflammatory Cytokines and White Blood Cell Counts Response to Environmental Levels of Diesel Exhaust and Ozone Inhalation Exposures. PLoS ONE. Public Library of Science, San Francisco, CA, USA, 11(4): e0152458, (2016).

Ozone Exposure During Implantation Increases Serum Bioactivity in HTR-8/SVneo Trophoblasts data. This dataset is associated with the following publication: Miller, C., E. Stewart, S. Snow, W. Williams, J. Richards, L. Thompson, M. Schladweiler, A. Farraj, U. Kodavanti, and J. Dye. Ozone exposure during implantation increases serum bioactivity in HTR8/SVneo trophoblasts. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 168(2): 535-550, (2019).

This data sets includes data shown in the Figures and Tables in the publication by Zhang et al (2018): https://doi.org/10.5194/acp-2018-498. This dataset is associated with the following publication: Zhang, Y., J.J. West, R. Mathur, J. Xing, C. Hogrefe, S. Roselle, J. Bash, J. Pleim, C. Gan, and D. Wong. Long-term trends in the ambient PM2.5- and O3-related mortality burdens in the United States under emission reductions from 1990 to 2010. Atmospheric Chemistry and Physics. Copernicus Publications, Katlenburg-Lindau, GERMANY, 18(20): 15003-15016, (2018).

This data set contains one Excel file. In this file are all the data pertaining to the effects of propranolol and mifepristone on ozone induced lung injury and inflammation . The different tabs of the spreadsheet pertain to each figure found in the manuscript. This dataset is associated with the following publication: Henriquez, A., S. Snow, M. Schladweiler, C. Miller, J. Dye, A. Ledbetter, J. Richards, K. Mauge-Lewis, M. McGee, and U. Kodavanti. Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 339: 161-171, (2018).