A 5-aminopyrazole of the formula in which R1 represents alkoxycarbonyl, alkenyloxycarbonyl or alkinyloxycarbonyl, and R3, R4, R5, R6, and R7, which are identical or different, represent hydrogen, halogen, cyano, nitro, alkyl, alkoxy, alkylsulphonyl, alkoxycarbonyl or a radical -(X)n-R8 wherein X represents oxygen, sulphur, sulphinyl or sulphyonyl, n represents 0 or 1 and R8 represents halogenoalkyl, with the proviso that at least one of the radicals R3, R4, R5, R6 or R7 represents a radical -(X)n-R8, and R1 does not represent cyano if R1 represents trifluoromethyl, These compounds are intermediates useful in the preparation of herbicidally active substituted 5-acylamino-1-phenylpyrazoles.

The invention discloses novel N-(2-nitrophenyl)-2-aminopyrimidine derivatives of the general formula I (I) wherein R1 and R2 are each independently NO2 or CF3, with the proviso that only R1 or R2 can be NO2 R3 is halogen, R4 is hydrogen or the -C(O)R' group, in which R' is C1-C4alkyl which is unsubstituted or substituted by halogen, C1-C3alkoxy or C1-C3alkylthio, R5, R6 and R7 are each independently hydrogen, halogen, nitro, cyano, thiocyano, C1-C12alkyl, C3-C8cycloalkyl, C1-C8alkylthio, C1-C6alkylsulfonyl, C1-C6alkylsulfoxyl, C3-C6alkenyl, C3-C6haloalkenyl, C3-C6alkynyl, C3-C6haloalkynyl, C3-C6alkenyloxy, C3-C6-haloalkenyloxy, C3-C6alkenylthio, C3-C6alkynyloxy, C3-C6haloalkynyloxy, C1-C8alkyl which is substituted by halogen, cyano and/or C1-C4alkoxy, unsubstituted C1-C8alkoxy or halogen-substituted C1-C8alkoxy, the alkyl moiety of which may be interrupted by one or more single oxygen atoms; or are the Q-(E)n-(X)m-group, in which n is 0 or 1, m is 0 or 1, Q is phenyl which is unsubstituted or substituted by halogen, nitro, C1-C3alkyl, CF3 and/or C1-C3 alkoxy, or is a saturated or unsaturated heterocyclic radical containing one or more hetero atoms, E is a C1-C3alkylene bridge, and X is oxygen or sulfur. Also disclosed are methods of preparing these compounds, and also agrochemical compositions which contain one such compound as active ingredient. The invention further relates to the use of the novel compounds, or, compositions containing them, in agriculture and related fields.

A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R<1> means substituted alkenyl, etc.; R<2> means substituted benzoyl, etc.; and R<3> to R<5> each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.

Thienothiophene derivatives of the formula I R1-(A1)m-Z1-A-(Z2-A2)n-R2 I in which R1 and R2 are each H or an alkyl group having 1-12 C atoms, in which, furthermore, one or two non-adjacent CH2 groups can be replaced by O atoms, -CO- or -CH=CH- groups, or are each F, Cl, Br, CN, -COOR or -O-COR, A1 and A2 are each 1,4-phenylene, 1,4-cyclohexylene, 1,3-dioxane-2,5-diyl, 1,3-dithiane-2,5-diyl, tetrahydropyran-2,5-diyl, pyridazine-3,6-diyl or the corresponding N-oxide, piperidine-1,4-diyl, 1,4-bicyclo[2.2.2]octylene or pyrimidine-2,5-diyl groups which are unsubstituted or substituted by one or two F, Cl or Br atoms and/or CN groups and/or CH3 groups, A is a group of the formula 1 or 2 which is unsubstituted or substituted by one or two Cl and/or Br atoms, Z1 and Z2 are each -CO-O-, -O-CO-, -CH2CH2-, -OCH2+13, -CH2O- or a single bond, R is an alkyl group having 1-10 C atoms, m is 1 or 2 and n is 0 or 1, and where m is 2, the two groups A1 can be identical or different, can be used as components of liquid crystalline phases.

The invention relates to new benzoylurea compounds having insecticidal and acaricidal activity, of the general formula wherein R1 is a hydrogen atom or represents 1 or 2 halogen atoms; Ar is a para-phenylene group or a para-pyridylene group, which groups may be substituted with 1 or 2 substituents selected from the group consisting of chlorine, methyl and trifluoromethyl; B is an oxygen atom or represents a group having the formula or wherein R2 is a hydrogen atom or an alkyl group having 1-4 carbon atoms; and R is a cycloalkyl group, a cycloalkenyl group having 6-12 carbon atoms, which groups may be substituted with 1-3 substituents selected from the group consisting of alkyl and alkenyl having 1-6 carbon atoms, or wherein R is a bi- or polycyclic, saturated or unsaturated, hydrocarbyl group, having 8-14 carbon atoms and, if desired, substituted with 1-3 substituents selected from the group consisting of alkyl and alkenyl having 1-6 carbon atoms; with the proviso, that, if Ar is a whether or not substituted paraphenylene group, and R is a whether or not substituted cyclohexylgroup, or a saturated bi- or polycyclic hydrocarbyl group having 8-14 carbon atoms. then B does not represent an oxygen atom.

The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R<1> and R<2> are each hydrogen or lower alkyl; R<3> R<4>, R<5> and R<6> are each hydrogen, halogen, lower alkyl or lower alkoxy; R<7> and R<8> are each hydrogen, halogen, lower alkyl, halo-lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, cyano, a hydroxyl group, lower acyl, carboxy or the like; R<9> is -C(O)-R<10>, -A<1>-C(O)-R<10>, -O-A<2>-C(O)-R<10> or a tetrazol-5-yl group, which exhibit potent and selective beta 3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.

N-(Azolylcarbamyl)-hydroxylamines of the formula (I) where R is unsubstituted or substituted alkyl, alkenyl, alkoxyalkyl or cycloalkyl, or unsubstituted or substituted phenyl, phenylalkyl, phenylalkenyl or phenoxyalkyl, R1 is alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl, cycloalkylalkyl or unsubstituted or substituted benzyl, Y is CH or N and R2 and R3 are each hydrogen or alkyl, and fungicides which contain these compounds.

1,4-Dihydropiridine derivatives having the formulawherein R is methyl, ethyl or isopropyl, are endowed with a hypotensive, vasodilator and Ca"-antagonistic activity.