Pyrimidine-5-carboxamide derivatives represented by a general formula (I) or salts thereof Äwherein each symbol has the following meaning; X: O, S, NR<1>, CO, NR<1>CO, CONR<1>, C=N-OR<1> or a bond, Y: a lower alkylene group which may be substituted by OR<1> or -NHR<1>, or a bond, Z: O, NR<2> or a bond, A: H, or a lower alkyl which may have a substituent, a -CO-lower alkyl which may have a substituent, an aryl which may have a substituent, a heteroaryl which may have a substituent, a cycloalkyl which may have a substituent or a nitrogen-containing saturated heterocyclic group which may have a substituent, B: an aryl which may have a substituent or a heteroaryl group which may have a substituent, R<1>, R<2>: H, a lower alkyl or a -CO-lower alkyl groupÜ.

3-Substituted 3,4-dihydrothieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof. The invention relates to 3,4-dihydrothieno[2,3-d]pyrimidin-4-one derivatives which are substituted in position 3 by 5-membered heteroaryl which may be fused to an aryl or heteroaryl radical, where the heteroaryl and, if appropriate, the fused aryl or heteroaryl radical may have 1, 2 or 3 substituents selected independently of one another from C1-5-alkyl, C1-5-alkoxy, C1-5-alkylthio, halogen, CN, halo-C1-5-alkyl, halo-C1-5-alkoxy, hydroxy, -NH2, -N(R6)2, -NH(R6), aryl, aryloxy, aralkyl, aralkyloxy and heteroaryl, where the substituents aryl, aryloxy, aralkyl, aralkyloxy and heteroaryl may have 1, 2 or 3 substituents selected independently of one another from C1-5-alkyl, C1-5-alkoxy, C1-5-alkylthio, halogen, CN, halo-C1-5-alkyl, halo-C1-5-alkoxy, hydroxy, -NH2, -N(R6)2 and -NH(R6). The preparation and use of these derivatives, especially for therapeutic purposes, e.g. for the treatment of depressions, are likewise described.

1. Claims for Contracting States BE, CH, DE, FR, GB, IT, LI, NL Compounds of the general formula I see diagramm : EP0096142,P25,F1 wherein R1 is a fragment [X, Y, Z(phenyl)], [X, Y, Z(biphenyl)], [U, V, W(pyridyl)], [U, V, W(furyl)] or [U, V, W(thienyl)], wherein X, Y and Z are each independently hydrogen, halogen, C1 -C4 alkyl, C1 -C3 haloalkyl, di(C1 -C4 alkyl)amino, nitro, cyano, -COO(C1 -C4 alkyl), -CON(C1 -C4 alkyl)2 or the group -E-R4 , wherein E is -O-, -S-, -SO- or -SO2 -, R4 is C1 -C6 alkyl which is unsubstituted or substituted by C1 -C4 alkoxy, unsubstituted C3 -C5 alkenyl, C3 -C5 alkynyl which is unsubstituted or substituted by halogen or hydroxy, or is [X, Y, Z(phenyl)] or -CH2 -[X, Y, Z-(phenyl)] ; U, V and W are each independently hydrogen, halogen or C1 -C4 alkyl ; R2 is -COO(C1 -C6 alkyl), -CO-(C1 -C6 alkyl), -CO-N(C1 -C6 alkyl)2 , cyano, nitro, -SO2 -(C1 -C6 alkyl), -P(O)-(C1 -C6 alkoxy)2 or -SO2 -N(C1 -C6 alkyl)2 ; and R3 is C1 -C3 haloalkyl. 1. Claims for Contracting State AT A microbicidal composition for controlling or preventing an attack on living plants and/or for preserving perishable storable goods of vegetable or animal origin, which composition contains, as at least one active component, one of the compounds of the general formula I see diagramm : EP0096142,P27,F1 wherein R1 is a fragment [X, Y, Z(phenyl)], [X, Y, Z(biphenyl)], [U, V, W(pyridyl)], [U, V, W(furyl)] or [U, V, W(thienyl)], wherein X, Y and Z are each independently hydrogen, halogen, C1 -C4 alkyl, C1 -C3 haloalkyl, di(C1 -C4 alkyl)amino, nitro, cyano, -COO(C1 -C4 alkyl), -CON(C1 -C4 alkyl)2 or the group -E-R4 , wherein E is -O-, -S-, -SO- or -SO2 -, R4 is unsubstituted C1 -C6 alkyl, C3 -C5 alkenyl which is unsubstituted or substituted by halogen, C3 -C5 alkynyl which is unsubstituted or substituted by halogen or hydroxy, or is [X, Y, Z(phenyl)] or -CH2 -[X, Y, Z(phenyl)] ; U, V and W are each independently hydrogen, halogen or C1 -C4 alkyl ; R2 is -COO(C1 -C6 alkyl), -CO-(C1 -C6 alkyl), -CO-N(C1 -C6 alkyl)2 , cyano, nitro, -SO2 -(C1 -C6 alkyl), -P(O)-(C1 -C6 alkoxy)2 or -SO2 -N(C1 -C6 alkyl)2 ; and R3 is C1 -C3 haloalkyl.

Chemical patent from PubChem database. Patent Number: AT-E400271-T1. Title: Bioactive Compound and Applications. Filing Date: 2011-12-19. Inventors: Yamamoto, Hiroshi, Schmidt, Hans. Abstract: A bioactive compound and its applications in pharmaceutical and agricultural fields are described. The compound exhibits significant biological activi... IPC Classifications: C07H, A61K, A61P. This patent covers 32 claims related to 4 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.

Herbicidally active 5-amino-1-phenylpyrazoles of the formula in which R is CN, or an ester or amido group, R1 is an organic radical, R2 is an organic radical, hydrogen or an acyl or thioacyl radical, R3, R4, R5, R6 and R7 can be hydrogen or various organic radicals but at least one is a haloalkyl, haloalkoxy, haloalkylthio, haloalkylsulphinyl or haloalkylsulphonyl radical, but R is not CN at the same time as R5 is CF3. The compounds are intermediates therefor and are also herbicidal.

1,4-Dihydropiridine derivatives having the formulawherein R is methyl, ethyl or isopropyl, are endowed with a hypotensive, vasodilator and Ca"-antagonistic activity.

Chemical patent from PubChem database. Patent Number: AT-E399767-T1. Title: Method of Treatment Using Chemical Compounds. Filing Date: 1995-07-14. Inventors: Kim, Young-Soo, Taylor, Elizabeth. Abstract: Methods for treating diseases using specific chemical compounds are provided, including dosing regimens and combination therapies for enhanced therape... IPC Classifications: C12N, C12P, A61K. This patent covers 38 claims related to 5 chemical compounds. Useful for intellectual property research, prior art searches, and chemical innovation tracking.