This dataset includes data used to generate Figures 4C, 5B, 5C, and 5D in Tal et al. Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity. Reproductive Toxicology. 2017. Data underlying all other figures shown in the manuscript are included in the Supplemental Tables published with the original article. This dataset is associated with the following publication: Tal , T., C. Kilty, A. Smith, C. LaLone , B. Kennedy, A. Tennant , C. McCollum, M. Bondesson, T. Knudsen , S. Padilla , and N. Kleinstreuer. Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 70: 70-81, (2017).

This dataset contains all underlying data used to generate the figures contained in Gaballah et al. Evaluation of developmental toxicity, developmental neurotoxicity, and tissue dose in zebrafish exposed to GenX and other PFAS. This dataset is associated with the following publication: Gaballah, S., A. Swank, X.M. Howey, J. Sobus, J. Schmid, T. Catron, J. McCord, E. Hines, and M. Strynar. Evaluation of developmental toxicity, developmental neurotoxicity, and tissue dose in zebrafish exposed to GenX and other PFAS. NA. NA (ed.), ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 128(4): 047005-1 - 047005-22, (2020).

Figure S1: BMC curves. Table S1: Fish assessments. Table S2: Data to make visualization of toxicity (Figure 3). Table S3: Data to make BMC curves. This dataset is associated with the following publication: Britton, K., R. Judson, B. Hill, K. Jarema, J. Olin, B. Knapp, M. Lowery, M. Feshuk, J. Brown, and S. Padilla. Using Zebrafish to Screen Developmental Toxicity of Per- and Polyfluoroalkyl Substances (PFAS). Toxics. MDPI, Basel, SWITZERLAND, 12(7): 501, (2024).

The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/toxics10050256/s1. Figure S1, Effect of DMSO on Light/Dark Locomotor Activity; Figure S2, Time Course Behavioral Graph, Activity Box Plots and Developmental Toxicity for each Chemical; Table S1, Raw Data. This dataset is associated with the following publication: Jarema, K., D. Hunter, B. Hill, J. Olin, K. Britton, M. Waalkes, and S. Padilla. Developmental Neurotoxicity and Behavioral Screening in Larval Zebrafish with a Comparison to Other Published Results. Toxics. MDPI, Basel, SWITZERLAND, 10(5): 256, (2022).

The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/toxics10050256/s1. Figure S1, Effect of DMSO on Light/Dark Locomotor Activity; Figure S2, Time Course Behavioral Graph, Activity Box Plots and Developmental Toxicity for each Chemical; Table S1, Raw Data. This dataset is associated with the following publication: Jarema, K., D. Hunter, B. Hill, J. Olin, K. Britton, M. Waalkes, and S. Padilla. Developmental Neurotoxicity and Behavioral Screening in Larval Zebrafish with a Comparison to Other Published Results. Toxics. MDPI, Basel, SWITZERLAND, 10(5): 256, (2022).

This file contains data used to generate figures shown in Catron et al. Characterization of host toxicity and microbiota disruption in larval zebrafish following developmental exposure to BPA and BPA alternatives. This dataset is associated with the following publication: Catron, T., S. Keely, N. Brinkman, T. Zurlinden, C. Wood, J. Wright, D. Phelps, E. Wheaton, A. Kvasnicka, S. Gaballah, R. Lamendella, and T. Tal. Host Developmental Toxicity of BPA and BPA Alternatives Is Inversely Related to Microbiota Disruption in Zebrafish. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(2): 468-483, (2019).

This file contains data used to generate figures shown in Catron et al. Characterization of host toxicity and microbiota disruption in larval zebrafish following developmental exposure to BPA and BPA alternatives. This dataset is associated with the following publication: Catron, T., S. Keely, N. Brinkman, T. Zurlinden, C. Wood, J. Wright, D. Phelps, E. Wheaton, A. Kvasnicka, S. Gaballah, R. Lamendella, and T. Tal. Host Developmental Toxicity of BPA and BPA Alternatives Is Inversely Related to Microbiota Disruption in Zebrafish. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(2): 468-483, (2019).

This study evaluated two anti-angiogenic agents, 5HPP-33 and TNP-470, across the ToxCastDB HTS assay platform and anchored the results to complex in vitro functional assays: the rat aortic explant assay (AEA), rat whole embryo culture (WEC), and the zebrafish embryotoxicity (ZET) assay. This dataset is not publicly accessible because: no EPA data; all the data generated by external organizations; EPA coauthors. It can be accessed through the following means: Data generated by external organizations. Format: N/A. This dataset is associated with the following publication: Ellis-Hutchings, R., R. Settivari, A. McCoy, N. Kleinstreuer, J. Franzosa, T. Knudsen, and E. Carney. (REPRODUCTIVE TOXICOLOGY) EMBRYONIC VASCULAR DISRUPTION ADVERSE OUTCOMES: LINKING HIGH THROUGHPUT SIGNALING SIGNATURES WITH FUNCTIONAL CONSEQUENCES. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 70: 82-96, (2017).

This study evaluated two anti-angiogenic agents, 5HPP-33 and TNP-470, across the ToxCastDB HTS assay platform and anchored the results to complex in vitro functional assays: the rat aortic explant assay (AEA), rat whole embryo culture (WEC), and the zebrafish embryotoxicity (ZET) assay. This dataset is not publicly accessible because: no EPA data; all the data generated by external organizations; EPA coauthors. It can be accessed through the following means: Data generated by external organizations. Format: N/A. This dataset is associated with the following publication: Ellis-Hutchings, R., R. Settivari, A. McCoy, N. Kleinstreuer, J. Franzosa, T. Knudsen, and E. Carney. (REPRODUCTIVE TOXICOLOGY) EMBRYONIC VASCULAR DISRUPTION ADVERSE OUTCOMES: LINKING HIGH THROUGHPUT SIGNALING SIGNATURES WITH FUNCTIONAL CONSEQUENCES. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 70: 82-96, (2017).

Data used to generate figures shown in Phelps et al. This dataset is associated with the following publication: Phelps, D., N. Brinkman, S. Keely, E. Anneken, T. Catron, D. Betancourt, C. Wood, S. Espenschied, J. Rawls, and T. Tal. Microbial colonization is required for normal neurobehavioral development in zebrafish. Scientific Reports. Nature Publishing Group, London, UK, 11(7): 11244, (2017).