Digital droplet PCR fluorsence amplitude values from which plasmid copy concentrations of DNA standards were determined as described in D-EMMD-MEB-018-SOP-01and Journal article. Summary of stability testing results also provided. This dataset is associated with the following publication: Sivaganesan, M., M. Varma, S. Siefring, and R. Haugland. Quantification of plasmid DNA standards for U.S. EPA fecal indicator bacteria qPCR methods by droplet digital PCR analysis. JOURNAL OF MICROBIOLOGICAL METHODS. Elsevier Science Ltd, New York, NY, USA, 152: 135-142, (2018).
Digital droplet PCR fluorsence amplitude values from which plasmid copy concentrations of DNA standards were determined as described in D-EMMD-MEB-018-SOP-01and Journal article. Summary of stability testing results also provided. This dataset is associated with the following publication: Sivaganesan, M., M. Varma, S. Siefring, and R. Haugland. Quantification of plasmid DNA standards for U.S. EPA fecal indicator bacteria qPCR methods by droplet digital PCR analysis. JOURNAL OF MICROBIOLOGICAL METHODS. Elsevier Science Ltd, New York, NY, USA, 152: 135-142, (2018).
Structural alerts for protein binding
공공데이터포털
The JRC dataset (doi: 10.1016/j.tiv.2016.07.014) includes reported outcomes in chemico, in vitro and in vivo tests for skin sensitisation. The Tox21 dataset was downloaded from the EPA CompTox Chemicals Dashboard (available at: https://comptox.epa.gov/dashboard/chemical_lists/TOX21SL) and was filtered to retain substances that were discrete organics with normalized structures, i.e. only substances that had an associated QSAR-ready SMILES record. This dataset is associated with the following publication: Nelms, M., R. Lougee, D. Roberts, A. Richard, and G. Patlewicz. Comparing and contrasting the coverage of publicly available structural alerts for protein binding. Computational Toxicology. Elsevier B.V., Amsterdam, NETHERLANDS, 12: 100100, (2019).
HTTK: R Package for High-Throughput Toxicokinetics
공공데이터포털
Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") as in Pearce et al. (2017) . Chemical-specific in vitro data have been obtained from relatively high throughput experiments. Both physiologically-based ("PBTK") and empirical (e.g., one compartment) "TK" models can be parameterized for several hundred chemicals and multiple species. These models are solved efficiently, often using compiled (C-based) code. This dataset is associated with the following publication: Pearce , R., C. Strope , W. Setzer , N. Sipes , and J. Wambaugh. (Journal of Statistical Software) HTTK: R Package for High-Throughput Toxicokinetics. Journal of Statistical Software. American Statistical Association, Alexandria, VA, USA, 79(4): 1-26, (2017).
Supplimental data
공공데이터포털
An Excel file including: raw data, data dictionary, and all final data sets. A PDF containing detailed equations for calculating the daily dose using the creatinine correction and UFR, figures comparing the HI between the creatinine correction and UFR, figures and tables comparing temporal trends in the MCR between the HI and potency-weighted approach, tables describing frequency of participants by cycle, temporal limit of detection by metabolite, tolerable daily intakes by phthalate, Group designation of the MCR, complete regression equations used in the regression analysis, comparison of Group counts by creatinine correction and UFR, and relative potency factors by phthalate. This dataset is associated with the following publication: Reyes, J., and P. Price. Temporal Trends in Exposures to Six Phthalates from Biomonitoring Data: Implications for Cumulative Risk. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 52(21): 12475-12483, (2018).
Dataset - Donner Nanosilver PCP Table 3 LCF results
공공데이터포털
Linear combination fitting results of the Ag K-edge XANES spectra using the standards listed, as percentage composition and variability (in parentheses) of the total. R-factor indicates the quality of the fit. This dataset is associated with the following publication: Khaksar, M., S. Vasileiadis, R. Sekine, G. Brunetti, K.G. Scheckel, K. Vasilev, E. Lombi, and E. Donner. Chemical characterisation, antibacterial activity, and (nano)silver transformation of commercial personal care products exposed to household greywater. Environmental Science: Nano. RSC Publishing, Cambridge, UK, 6(10): 3027-3028, (2019).
Dataset - Donner Nanosilver PCP Table 3 LCF results
공공데이터포털
Linear combination fitting results of the Ag K-edge XANES spectra using the standards listed, as percentage composition and variability (in parentheses) of the total. R-factor indicates the quality of the fit. This dataset is associated with the following publication: Khaksar, M., S. Vasileiadis, R. Sekine, G. Brunetti, K.G. Scheckel, K. Vasilev, E. Lombi, and E. Donner. Chemical characterisation, antibacterial activity, and (nano)silver transformation of commercial personal care products exposed to household greywater. Environmental Science: Nano. RSC Publishing, Cambridge, UK, 6(10): 3027-3028, (2019).