biological relevance of reductions of testosterone production on the adverse effects of in utero phthalate combinations

공공데이터포털

RAW DATA, SAS FILES AND DATA MEANS. This dataset is associated with the following publication: Howdeshell, K., C. Rider, V. Wilson , J. Furr , C. Lambright , and E. Gray. Dose addition models based on biologically-relevant reductions in fetal testosterone accurately predict postnatal reproductive tract alterations by a phthalate mixture in rats. TOXICOLOGICAL SCIENCES. Society of Toxicology, 148(2): 488-502, (2015).

Establishing the “Biological Relevance” of Dipentyl Phthalate Reductions in Fetal Rat Testosterone Production and Plasma and Testis Testosterone Levels

공공데이터포털

metadata sheet, data sheet for each table and figure in the published manuscript. This dataset is associated with the following publication: Gray , E., J. Furr , K. Tatum-Gibbs, C. Lambright , H. Sampson, B. Hannas, V. Wilson , A. Hotchkiss , and P. Foster. Establishing the Biological Relevance of Dipentyl Phthalate Reductions in Fetal Rat Testosterone Production and Plasma and Testis Testosterone Levels. TOXICOLOGICAL SCIENCES. Society of Toxicology, 149(1): 178-91, (2016).

Establishing the “Biological Relevance” of Dipentyl Phthalate Reductions in Fetal Rat Testosterone Production and Plasma and Testis Testosterone Levels

공공데이터포털

metadata sheet, data sheet for each table and figure in the published manuscript. This dataset is associated with the following publication: Gray , E., J. Furr , K. Tatum-Gibbs, C. Lambright , H. Sampson, B. Hannas, V. Wilson , A. Hotchkiss , and P. Foster. Establishing the Biological Relevance of Dipentyl Phthalate Reductions in Fetal Rat Testosterone Production and Plasma and Testis Testosterone Levels. TOXICOLOGICAL SCIENCES. Society of Toxicology, 149(1): 178-91, (2016).

genomic and endocrine effects of in utero p[hthalates

공공데이터포털

effects of in utero phthalate and other chemical administration on male rat sexual differentiation: Non PPAR mediated AOP. This dataset is associated with the following publication: Gray, E., J. Conley, C. Lambright, N. Evans, J. Furr, V. Wilson, B. Hannas, P. Foster, and H. Sampson. Genomic and Hormonal Biomarkers of Phthalate-induced Male Rat Reproductive Developmental Toxicity: Part II A Targeted RT-qPCR Array Approach that Defines a Unique Adverse Outcome Pathway.. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 182(2): 195-214, (2021).

genomic and endocrine effects of in utero p[hthalates

공공데이터포털

effects of in utero phthalate and other chemical administration on male rat sexual differentiation: Non PPAR mediated AOP. This dataset is associated with the following publication: Gray, E., J. Conley, C. Lambright, N. Evans, J. Furr, V. Wilson, B. Hannas, P. Foster, and H. Sampson. Genomic and Hormonal Biomarkers of Phthalate-induced Male Rat Reproductive Developmental Toxicity: Part II A Targeted RT-qPCR Array Approach that Defines a Unique Adverse Outcome Pathway.. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 182(2): 195-214, (2021).

Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells

공공데이터포털

the dataset contains NHEERL collected data on fetal male rat gestational day 18 testicular testosterone production and related data. This dataset is associated with the following publication: spade, d., C. Yue Bai , C. Lambright, J. Conley, K. Boekelheide , and E. Gray. Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, USA, 290: 55-61, (2018).

Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells

공공데이터포털

the dataset contains NHEERL collected data on fetal male rat gestational day 18 testicular testosterone production and related data. This dataset is associated with the following publication: spade, d., C. Yue Bai , C. Lambright, J. Conley, K. Boekelheide , and E. Gray. Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, USA, 290: 55-61, (2018).

Dataset for manuscript "Mixed “anti-androgenic” chemicals at low individual doses produces reproductive tract malformations in the male rat"

공공데이터포털

Dataset contains summary data (mean, standard error, sample size (n)) for all measured endpoints reported and depicted in the corresponding manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, M. Cardon, J. Furr, V. Wilson, and E. Gray. Mixed “antiandrogenic” chemicals at low individual doses produce reproductive tract malformations in the male rat. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 164(1): 166-178, (2018).

Dataset for manuscript "Mixed “anti-androgenic” chemicals at low individual doses produces reproductive tract malformations in the male rat"

공공데이터포털

Dataset contains summary data (mean, standard error, sample size (n)) for all measured endpoints reported and depicted in the corresponding manuscript. This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, M. Cardon, J. Furr, V. Wilson, and E. Gray. Mixed “antiandrogenic” chemicals at low individual doses produce reproductive tract malformations in the male rat. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 164(1): 166-178, (2018).

The Application of a Highly Purified Rat Leydig Cell Assay as a Complement to the H295R Steroidogenesis Assay to Evaluate Toxicant Induced Alterations in Testosterone Production

공공데이터포털

The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not detected by the high throughput screening format of the H295R steroidogenesis assay. This dataset is associated with ORD-022468 entered in STICS. This dataset is associated with the following publication: Botteri Principato, N., J. Suarez, S. Laws, and G. Klinefelter. The Use of Purified Rat Leydig Cells Complements the H295R Screen to Detect Chemical Induced Alterations in Testosterone Production. BIOLOGY OF REPRODUCTION. Society for the Study of Reproduction, 98(2): 239-249, (2018).