Compares results of bioassay with hormones measured using analytical chemistry. This dataset is associated with the following publication: Conley, J., H. Mash , N. Evans , K. Schenck , L. Rosenblum, S. Glassmeyer , E.T. Furlong, D.W. Kolpin, and V. Wilson. Comparison of in vitro estrogenic activity and estrogen concentrations in source and treated waters from 25 U.S. drinking water treatment plants. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, N/A, (2016).

In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a nationwide screen of United States stream water samples. In vitro bioassays include T47D-Kbluc, MDA-kb2, and a CV-1 cell line transduced with human glucocorticoid receptor. This dataset is associated with the following publication: Conley, J., N. Evans, M. Cardon, L. Rosenblum, L. Iwanowicz, P. Hartig, K. Schenck, P. Bradley, and V. Wilson. Occurrence and in vitro bioactivity of estrogen, androgen, and glucocorticoid compounds in a nationwide screen of United States stream waters. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 4781-4791, (2017).

In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a nationwide screen of United States stream water samples. In vitro bioassays include T47D-Kbluc, MDA-kb2, and a CV-1 cell line transduced with human glucocorticoid receptor. This dataset is associated with the following publication: Conley, J., N. Evans, M. Cardon, L. Rosenblum, L. Iwanowicz, P. Hartig, K. Schenck, P. Bradley, and V. Wilson. Occurrence and in vitro bioactivity of estrogen, androgen, and glucocorticoid compounds in a nationwide screen of United States stream waters. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 4781-4791, (2017).

Intersex in small- and largemouth bass has been observed in the upper Chesapeake Bay Watershed since 2003. This observation is indicative of exposure to estrogenic endocrine disrupting chemicals. In order to complement biological data sets and better identify the spatial and temporal nature of this end-point, discrete grab water samples were collected throughout the upper Chesapeake Bay Watershed for the evaluation of estrogenic activity. Data reported here are estrogenicity values derived from bioassay screening of OASIS-HLB extracts discrete grab water samples. Estrogenicity was determined using a bioluminescent yeast estrogen screen. Here we report estrogenicity data for selected sites in the Chesapeake Bay water shed collected between 2008 and 2011.

Intersex in small- and largemouth bass has been observed in the upper Chesapeake Bay Watershed since 2003. This observation is indicative of exposure to estrogenic endocrine disrupting chemicals. In order to complement biological data sets and better identify the spatial and temporal nature of this end-point, discrete grab water samples were collected throughout the upper Chesapeake Bay Watershed for the evaluation of estrogenic activity. Data reported here are estrogenicity values derived from bioassay screening of OASIS-HLB extracts discrete grab water samples. Estrogenicity was determined using a bioluminescent yeast estrogen screen. Here we report estrogenicity data for selected sites in the Chesapeake Bay water shed collected between 2008 and 2011.

The data were gathered as part of a long-term, seasonal assessment of estrogenicity in selected locations within Pennsylvania from 2012-2017. Data were collected over this time frame to determine seasonal and annual changes in surface water estrogenicity.Estrogen is reported as estrogen equivalents (EEQ) as determined by a bioluminescent yeast estrogen screen. A total of 193 grab water samples were collected during this time of which 41% had EEQ above the limit of detection. The maximum estrogen equivalents (EEQ) measured was 5.44 ng EEQ/ L, while the median concentration was 0.44 ng/L. POCIS samplers were deployed at a number of sites to determine time-weighted estrogenicity between 2014 and 2017. A total of 150 POCIS samples were deployed over this time of which 77% had EEQ above the limit of detection.. The maximum estrogen equivalents (EEQ) measured was 12 ng EEQ/ POCIS.

The data were gathered as part of a long-term, seasonal assessment of estrogenicity in selected locations within Pennsylvania from 2012-2017. Data were collected over this time frame to determine seasonal and annual changes in surface water estrogenicity.Estrogen is reported as estrogen equivalents (EEQ) as determined by a bioluminescent yeast estrogen screen. A total of 193 grab water samples were collected during this time of which 41% had EEQ above the limit of detection. The maximum estrogen equivalents (EEQ) measured was 5.44 ng EEQ/ L, while the median concentration was 0.44 ng/L. POCIS samplers were deployed at a number of sites to determine time-weighted estrogenicity between 2014 and 2017. A total of 150 POCIS samples were deployed over this time of which 77% had EEQ above the limit of detection.. The maximum estrogen equivalents (EEQ) measured was 12 ng EEQ/ POCIS.

This data set includes results for hormone and pharmaceutical compounds analyzed in environmental and quality-control samples collected by the USGS National Water-Quality Assessment Project during 2013 through 2015 for a study of groundwater resources used for drinking-water supply across the United States. This data release includes: Table 1. Site information and ancillary data (including principal aquifer, rock type, well depth, groundwater age information, aridity information, and land-use information) for groundwater sites sampled for hormones and pharmaceuticals by the National Water-Quality Assessment Project, 2013-15. Table 2. Hormone and pharmaceutical results for groundwater samples collected by the National Water-Quality Assessment Project, 2013-15. Table 3. Hormone and pharmaceutical results for field related blank samples of known blank type collected by the National Water-Quality Assessment Project for groundwater, 2013-15. Table 4. Hormone and pharmaceutical results for laboratory matrix spikes and associated environmental samples collected by the National Water-Quality Assessment Project for groundwater, 2013-15. Table 5. Hormone and pharmaceutical results for replicate samples and associated environmental samples collected by the National Water-Quality Assessment Project for groundwater, 2013-15.

This data set includes results for hormone and pharmaceutical compounds analyzed in environmental and quality-control samples collected by the USGS National Water-Quality Assessment Project during 2013 through 2015 for a study of groundwater resources used for drinking-water supply across the United States. This data release includes: Table 1. Site information and ancillary data (including principal aquifer, rock type, well depth, groundwater age information, aridity information, and land-use information) for groundwater sites sampled for hormones and pharmaceuticals by the National Water-Quality Assessment Project, 2013-15. Table 2. Hormone and pharmaceutical results for groundwater samples collected by the National Water-Quality Assessment Project, 2013-15. Table 3. Hormone and pharmaceutical results for field related blank samples of known blank type collected by the National Water-Quality Assessment Project for groundwater, 2013-15. Table 4. Hormone and pharmaceutical results for laboratory matrix spikes and associated environmental samples collected by the National Water-Quality Assessment Project for groundwater, 2013-15. Table 5. Hormone and pharmaceutical results for replicate samples and associated environmental samples collected by the National Water-Quality Assessment Project for groundwater, 2013-15.

This data set includes results for hormone and pharmaceutical compounds analyzed from 2012 through 2016 in laboratory quality-control samples that are associated with environmental samples collected by the National Water-Quality Assessment (NAWQA) Project during 2013 through 2015 for a study of groundwater resources used for drinking-water supply across the United States. Hormone and pharmaceutical results are provided for laboratory set blanks and reagent spikes analyzed during a time period that encompasses laboratory analysis of the environmental samples collected by NAWQA. This data release includes: Table 1. Hormone results for laboratory set blanks, December 18, 2012 through March 7, 2016. Table 2. Pharmaceutical results for laboratory set blanks, December 14, 2012 through March 4, 2016. Table 3. Hormone results for laboratory reagent spikes, June 17, 2013 through December 11, 2015. Table 4. Pharmaceutical results for laboratory reagent spikes, June 18, 2013 through October 1, 2015.